Volume 51, Issue 9 pp. 805-814
Article
Free Access

Study of the Effect of Vaccination on Periodic Structures of Measles Epidemics in Japan

Ayako Sumi

Corresponding Author

Ayako Sumi

Department of Hygiene, Sapporo Medical University School of Medicine, Sapporo, Hokkaido, 060-8556 Japan

Address correspondence to Dr. Ayako Sumi, Department of Hygiene, Sapporo Medical University School of Medicine, S-1, W-17, Chuo-ku, Sapporo, 060-8556, Japan. Fax: + 81-11-612-1660. E-mail: [email protected]Search for more papers by this author
Ken-ichi Kamo

Ken-ichi Kamo

Liberal Arts and Science Division of Mathematics, Sapporo Medical University School of Medicine, Sapporo, Hokkaido, 060-8556 Japan

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Norio Ohtomo

Norio Ohtomo

Faculty of Engineering, Hokkaido University, Sapporo, Hokkaido, 060-8628 Japan

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Nobumichi Kobayashi

Nobumichi Kobayashi

Department of Hygiene, Sapporo Medical University School of Medicine, Sapporo, Hokkaido, 060-8556 Japan

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First published: 14 November 2013
Citations: 12

Abstract

The purpose of this paper is to investigate the effect of vaccination on periodic structures of measles epidemics in Japan. We carried out spectral analysis for time series data of measles notifications collected in Japan. It was confirmed that the interepidemic period, which corresponds to the interval between major epidemics of measles, increases as the vaccination ratio increases. This result was supported by a theory based on a mathematical model for epidemics of infectious diseases. It was suggested that the interepidemic period is useful to estimate the effect of vaccination on measles incidences quantitatively.

Abbreviations

  • FFT
  • fast Fourier transform
  • MEM
  • maximum entropy method
  • MMR, measles
  • mumps and rubella
  • PSD
  • power spectral density
  • SEIR
  • Susceptibles/Exposed/Infectives/Recovers
  • S/N
  • signal-to-noise.
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