Volume 45, Issue 12 pp. 1640-1644

High-grade Atrioventricular Block Triggered by Spontaneous and Stimulation-induced Epileptic Activity in the Left Temporal Lobe

Dirk-Matthias Altenmüller

Dirk-Matthias Altenmüller

Epilepsy Center

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Manfred Zehender

Manfred Zehender

Department of Cardiology, University of Freiburg, Freiburg, Germany

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Andreas Schulze-Bonhage

Andreas Schulze-Bonhage

Epilepsy Center

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First published: 29 November 2004
Citations: 60
Address correspondence and reprint requests to Dr. D.-M. Altenmüller at Sektion Prächirurgische Epilepsiediagnostik am Neurozentrum Freiburg, Breisacher Strasse 64, 79106 Freiburg, Germany. E-mail: [email protected]

Abstract

Summary: Cardiac bradyarrhythmias may play a pivotal role in the pathophysiology of sudden unexpected death in epilepsy (SUDEP). We describe a patient with left temporal lobe epilepsy in whom high-grade atrioventricular conduction blocks were triggered by both spontaneous and stimulation-induced epileptic activity in the left temporal lobe. Electrophysiological data obtained by surface and intracranial electrodes point to a cerebral cardioarrhythmogenesis in the left amygdala and anterior hippocampus.

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