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ORIGINAL ARTICLE

Evaluating the Effectiveness of Virtual Reality in Reducing Dental Anxiety in Children Aged 6–12: A Randomized Clinical Trial

Mohammad Reza Mir Mohammadi

Mohammad Reza Mir Mohammadi

Health Information Management Research Center, Kashan University of Medical Sciences, Kashan, Iran

Department of Health Information Technology and Management, School of Allied-Medical Sciences, Kashan University of Medical Sciences, Kashan, Iran

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Leila Shokrizadeh Arani

Leila Shokrizadeh Arani

Health Information Management Research Center, Kashan University of Medical Sciences, Kashan, Iran

Department of Health Information Technology and Management, School of Allied-Medical Sciences, Kashan University of Medical Sciences, Kashan, Iran

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Amene Taghdisi Kashani

Amene Taghdisi Kashani

Department of Pediatric, Faculty of Dentistry, Kashan University of Medical Sciences, Kashan, Iran

Research Committee, Kashan University of Medical Sciences, Kashan, Iran

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Siavash Amiri

Siavash Amiri

Department of Clinical Biochemistry, Faculty of Medicine, Kashan University of Medical Sciences, Kashan, Iran

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Ali Mohammad Nickfarjam

Corresponding Author

Ali Mohammad Nickfarjam

Health Information Management Research Center, Kashan University of Medical Sciences, Kashan, Iran

Department of Health Information Technology and Management, School of Allied-Medical Sciences, Kashan University of Medical Sciences, Kashan, Iran

Correspondence:

Ali Mohammad Nickfarjam ([email protected])

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First published: 03 July 2025

Funding: The authors received no specific funding for this work.

ABSTRACT

Background

VR is an emerging technology in healthcare, including dentistry, where it seeks to enhance patient comfort and treatment outcomes, and provide distraction through creating an immersive environment.

Aim

To assess VR's impact on anxiety in children (6–12 years) during dental treatments with local anesthesia.

Design

In this clinical trial, we assessed anxiety levels in children (6–12 years) undergoing local anesthetic dental procedures using VR animation. Initially, we utilized the Screen for Child Anxiety-Related Disorders (SCARED) questionnaire for patient selection, in which 44 children were recruited, but eight were excluded, leaving 36 participants who were randomly assigned to either a VR group or a control group with no VR (18 participants each). Anxiety was measured using the MCDAS(f) questionnaire, along with heart rate and oxygen saturation.

Results

The results demonstrated that VR significantly reduced anxiety, as reflected in lower MCDAS(f) scores. Moreover, heart rate reductions were notably greater in the VR group compared to the control group (p < 0.001 for both measures), indicating a clear decrease in anxiety.

Conclusions

VR shows promise for reducing dental anxiety and improving treatment outcomes, though additional research is needed to assess its long-term effects. The incorporation of VR in routine pediatric dental care may improve child cooperation and reduce reliance on pharmacological sedation.

Conflicts of Interest

The authors declare no conflicts of interest.

Data Availability Statement

All data are included in the published manuscript.

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