Body composition and bone mineral density in breast cancer survivors and non-cancer controls: A 12- to 15-month follow-up
Corresponding Author
A.L. Artese
Department of Nutrition, Food and Exercise Sciences, College of Human Sciences, Florida State University, Tallahassee, FL, USA
Correspondence
Ashley L. Artese, Department of Nutrition, Food and Exercise Sciences, Florida State University, Tallahassee, FL, USA.
Email: [email protected]
Search for more papers by this authorE. Simonavice
School of Health and Human Performance, Georgia College & State University, Milledgeville, GA, USA
Search for more papers by this authorT.A. Madzima
Department of Exercise Science, Elon University, Elon, NC, USA
Search for more papers by this authorJ.-S. Kim
Department of Nutrition, Food and Exercise Sciences, College of Human Sciences, Florida State University, Tallahassee, FL, USA
Center for Advancing Exercise and Nutrition Research on Aging, Florida State University, Tallahassee, FL, USA
Institute for Successful Longevity, Florida State University, Tallahassee, FL, USA
Search for more papers by this authorB.H. Arjmandi
Department of Nutrition, Food and Exercise Sciences, College of Human Sciences, Florida State University, Tallahassee, FL, USA
Center for Advancing Exercise and Nutrition Research on Aging, Florida State University, Tallahassee, FL, USA
Search for more papers by this authorJ.Z. Ilich
Department of Nutrition, Food and Exercise Sciences, College of Human Sciences, Florida State University, Tallahassee, FL, USA
Search for more papers by this authorL.B. Panton
Department of Nutrition, Food and Exercise Sciences, College of Human Sciences, Florida State University, Tallahassee, FL, USA
Institute for Successful Longevity, Florida State University, Tallahassee, FL, USA
Search for more papers by this authorCorresponding Author
A.L. Artese
Department of Nutrition, Food and Exercise Sciences, College of Human Sciences, Florida State University, Tallahassee, FL, USA
Correspondence
Ashley L. Artese, Department of Nutrition, Food and Exercise Sciences, Florida State University, Tallahassee, FL, USA.
Email: [email protected]
Search for more papers by this authorE. Simonavice
School of Health and Human Performance, Georgia College & State University, Milledgeville, GA, USA
Search for more papers by this authorT.A. Madzima
Department of Exercise Science, Elon University, Elon, NC, USA
Search for more papers by this authorJ.-S. Kim
Department of Nutrition, Food and Exercise Sciences, College of Human Sciences, Florida State University, Tallahassee, FL, USA
Center for Advancing Exercise and Nutrition Research on Aging, Florida State University, Tallahassee, FL, USA
Institute for Successful Longevity, Florida State University, Tallahassee, FL, USA
Search for more papers by this authorB.H. Arjmandi
Department of Nutrition, Food and Exercise Sciences, College of Human Sciences, Florida State University, Tallahassee, FL, USA
Center for Advancing Exercise and Nutrition Research on Aging, Florida State University, Tallahassee, FL, USA
Search for more papers by this authorJ.Z. Ilich
Department of Nutrition, Food and Exercise Sciences, College of Human Sciences, Florida State University, Tallahassee, FL, USA
Search for more papers by this authorL.B. Panton
Department of Nutrition, Food and Exercise Sciences, College of Human Sciences, Florida State University, Tallahassee, FL, USA
Institute for Successful Longevity, Florida State University, Tallahassee, FL, USA
Search for more papers by this authorAbstract
While prognosis for breast cancer in women has improved, adverse side effects of treatments may negatively affect body composition and bone mineral density (BMD). This study assessed body composition and BMD changes in breast cancer survivors (BCS) (n = 10, 57.9 ± 5.7 years) and age-matched women (non-cancer, n = 10, 56.5 ± 4.3 years) over a 12- to 15-month period via dual-energy X-ray absorptiometry. No differences were observed between groups at baseline except forearm BMD values were lower in BCS (BCS: 0.462 ± 0.070 g/cm2; Control: 0.539 ± 0.052 g/cm2, p = .012). Body fat increased in both groups compared to baseline (BCS: 38.3–39.6 kg, p = .013; Control: 38.2–39.5 kg, p = .023) at the follow-up. Significant decreases in BMD at the lumbar spine, femoral neck, total femur and ulna were observed in both groups. Breast cancer survivors had a greater decrease in left femoral neck BMD. While BCS demonstrated lower baseline forearm BMD values and a greater decrease in left femoral neck BMD, both groups showed an increase in body fat and decrease in forearm BMD. These findings support the implementation of interventions to improve body composition and BMD in both BCS and women without cancer.
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