Volume 32, Issue 4 e12981
Original Paper

Serpentine supravenous hyperpigmentation related to carboplatin and vinorelbine chemotherapy: A case report

Fatma Tuncez Akyurek

Corresponding Author

Fatma Tuncez Akyurek

Faculty of Medicine, Department of Dermatology, Selcuk University, Konya, Turkey

Correspondence

Fatma Tuncez Akyurek, Faculty of Medicine, Department of Dermatology, Selcuk University, Konya, Turkey.

Email: [email protected]

Search for more papers by this author
Nihal Sari

Nihal Sari

Faculty of Medicine, Department of Dermatology, Selcuk University, Konya, Turkey

Search for more papers by this author
Ceyhan Ugurluoglu

Ceyhan Ugurluoglu

Faculty of Medicine, Department of Pathology, Selcuk University, Konya, Turkey

Search for more papers by this author
Gulcan Saylam Kurtipek

Gulcan Saylam Kurtipek

Faculty of Medicine, Department of Dermatology, Selcuk University, Konya, Turkey

Search for more papers by this author
First published: 06 June 2019
Citations: 6

Abstract

Serpentine supravenous hyperpigmentation (SSH) is a unique type of chemotherapy-associated drug eruption, characterized by hyperpigmentation along the superficial venous network. Histopathology reveals an increase in melanin production without destruction of basal cells of the epidermis or dermal inflammatory infiltrate. Herein, we describe a patient who developed SSH after repeated intravenous infusions with carboplatin and vinorelbine; two medications that have been uncommonly reported in association with SSH previously.

The full text of this article hosted at iucr.org is unavailable due to technical difficulties.