Volume 32, Issue 4 e12832
Special Issue Article

Rapid remission of Stevens–Johnson syndrome by combination therapy using etanercept and intravenous immunoglobulin and a review of the literature

Ruojun Wang

Ruojun Wang

Department of Dermatology, Peking University First Hospital, Beijing, China

Beijing Key Laboratory of Molecular Diagnosis on Dermatoses, Beijing, China

Research Center for Medical Mycology, Peking University, Beijing, China

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Shaomin Zhong

Shaomin Zhong

Department of Dermatology, Peking University First Hospital, Beijing, China

Beijing Key Laboratory of Molecular Diagnosis on Dermatoses, Beijing, China

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Ping Tu

Ping Tu

Department of Dermatology, Peking University First Hospital, Beijing, China

Beijing Key Laboratory of Molecular Diagnosis on Dermatoses, Beijing, China

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Ruoyu Li

Ruoyu Li

Department of Dermatology, Peking University First Hospital, Beijing, China

Beijing Key Laboratory of Molecular Diagnosis on Dermatoses, Beijing, China

Research Center for Medical Mycology, Peking University, Beijing, China

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Mingyue Wang

Corresponding Author

Mingyue Wang

Department of Dermatology, Peking University First Hospital, Beijing, China

Beijing Key Laboratory of Molecular Diagnosis on Dermatoses, Beijing, China

Correspondence

Mingyue Wang, Department of Dermatology, Peking University First Hospital, Beijing 100034, China.

Email: [email protected]

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First published: 18 January 2019
Citations: 18

Abstract

Stevens–Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) are spectrum of rare, acute, and life-threatening delayed-type drug hypersensitivity reactions that are associated with high mortality rates. However, no therapeutic standard has been proposed for SJS/TEN. Here, we report a case of a patient diagnosed with Stevens–Johnson syndrome whose disease progression was halted by a single dose of etanercept and was treated successfully. In addition, we reviewed the literature reporting patients with SJS/TEN treated with similar regimens.

CONFLICT OF INTEREST

None reported.

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