CD30+ lymphoproliferative disorder with spindle-cell morphology
Kathryn J. Martires
The Ronald O. Perelman Department of Dermatology, New York University School of Medicine, New York, NY, USA
Search for more papers by this authorBrandon E. Cohen
Department of Dermatology, New York University, School of Medicine, New York, NY, USA
Search for more papers by this authorCorresponding Author
David S. Cassarino
Department of Pathology, Kaiser Permanente Los Angeles Medical Center, Los Angeles, CA, USA
David S. Cassarino, MD. PhD,
Southern California Permanente Medical Group, Sunset Medical Center, Department of Pathology, 4867 Sunset Blvd, 2nd floor, Los Angeles, CA 90027 USA
Tel: +323 783 3595
Fax: +323 783 7825
e-mail: [email protected]
Search for more papers by this authorKathryn J. Martires
The Ronald O. Perelman Department of Dermatology, New York University School of Medicine, New York, NY, USA
Search for more papers by this authorBrandon E. Cohen
Department of Dermatology, New York University, School of Medicine, New York, NY, USA
Search for more papers by this authorCorresponding Author
David S. Cassarino
Department of Pathology, Kaiser Permanente Los Angeles Medical Center, Los Angeles, CA, USA
David S. Cassarino, MD. PhD,
Southern California Permanente Medical Group, Sunset Medical Center, Department of Pathology, 4867 Sunset Blvd, 2nd floor, Los Angeles, CA 90027 USA
Tel: +323 783 3595
Fax: +323 783 7825
e-mail: [email protected]
Search for more papers by this authorAbstract
Lymphomatoid papulosis (LyP) is classified as a CD30+ primary cutaneous lymphoproliferative disease. The phenotypic variability along the spectrum of CD30+ lymphoproliferative diseases is highlighted by the distinct histologic subtypes of LyP types A, B, C, and the more recently described types D, E, and F. We report the case of an elderly woman with a clinical presentation and histopathologic findings consistent with LyP, whose atypical CD30+ infiltrate uniquely demonstrated a spindle-cell morphology. To our knowledge, this is the first reported case of LyP characterized by CD30+ spindle-shaped cells, and may represent a new and distinct histologic variant of LyP.
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