Evaluation of alveolar ridge preservation in sockets with buccal dehiscence defects using two types of xenogeneic biomaterials: An in vivo experimental study
Hee-seung Han
Department of Periodontology, School of Dentistry and Dental Research Institute, Seoul National University and Seoul National University Dental Hospital, Seoul, Republic of Korea
Search for more papers by this authorJung-Tae Lee
One-Stop Specialty Center, Seoul National University, Dental Hospital, Seoul, Republic of Korea
Search for more papers by this authorSeunghan Oh
Department of Dental Biomaterials, The Institute of Biomaterial and Implant, School of Dentistry, Wonkwang University, Iksan, Republic of Korea
Search for more papers by this authorYoung-Dan Cho
Department of Periodontology, School of Dentistry and Dental Research Institute, Seoul National University and Seoul National University Dental Hospital, Seoul, Republic of Korea
Search for more papers by this authorCorresponding Author
Sungtae Kim
Department of Periodontology, School of Dentistry and Dental Research Institute, Seoul National University and Seoul National University Dental Hospital, Seoul, Republic of Korea
Correspondence
Sungtae Kim, Department of Periodontology, School of Dentistry, Seoul National University, 101 Daehak-ro, Jongno-gu, Seoul 03080, Republic of Korea.
Email: [email protected]
Search for more papers by this authorHee-seung Han
Department of Periodontology, School of Dentistry and Dental Research Institute, Seoul National University and Seoul National University Dental Hospital, Seoul, Republic of Korea
Search for more papers by this authorJung-Tae Lee
One-Stop Specialty Center, Seoul National University, Dental Hospital, Seoul, Republic of Korea
Search for more papers by this authorSeunghan Oh
Department of Dental Biomaterials, The Institute of Biomaterial and Implant, School of Dentistry, Wonkwang University, Iksan, Republic of Korea
Search for more papers by this authorYoung-Dan Cho
Department of Periodontology, School of Dentistry and Dental Research Institute, Seoul National University and Seoul National University Dental Hospital, Seoul, Republic of Korea
Search for more papers by this authorCorresponding Author
Sungtae Kim
Department of Periodontology, School of Dentistry and Dental Research Institute, Seoul National University and Seoul National University Dental Hospital, Seoul, Republic of Korea
Correspondence
Sungtae Kim, Department of Periodontology, School of Dentistry, Seoul National University, 101 Daehak-ro, Jongno-gu, Seoul 03080, Republic of Korea.
Email: [email protected]
Search for more papers by this authorYoung-Dan Cho and Sungtae Kim contributed equally to this work.
Abstract
Objectives
Alveolar ridge preservation (ARP) has been extensively investigated in various preclinical and clinical studies, yielding favorable results. We aim to evaluate the effects of ARP using collagenated bovine bone mineral (CBBM) alone or particulated bovine bone mineral with a non-cross-linked collagen membrane (PBBM/NCLM) in tooth extraction sockets with buccal dehiscence in an experimental dog model.
Materials and Methods
The mesial roots of three mandibular premolars (P2, P3, and P4) were extracted from six mongrel dogs 4 weeks after inducing dehiscence defects. ARP was randomly performed using two different protocols: 1) CBBM alone and 2) PBBM/NCLM. Three-dimensional (3D) volumetric, micro-computed tomography, and histological analyses were employed to determine changes over a span of 20 weeks.
Results
In 3D volumetric and radiographic analyses, CBBM alone demonstrated similar effectiveness to PBBM/NCLM in ARP (p > .05). However, in the PBBM/NCLM group (3.05 ± 0.60 mm), the horizontal ridge width was well maintained 3 mm below the alveolar crest compared with the CBBM group (2.11 ± 1.01 mm, p = .002).
Conclusion
Although the radiographic changes in the quality and quantity of bone were not significant between the two groups, the use of PBBM/NCLM resulted in greater horizontal dimensions and more favorable maintenance of the ridge profile.
CONFLICT OF INTEREST STATEMENT
The authors declare there are no potential conflicts of interest regarding authorship and/or publication of this article.
Open Research
DATA AVAILABILITY STATEMENT
All data generated by this study are included in this manuscript.
Supporting Information
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| clr14169-sup-0001-Figures.pptxPowerPoint 2007 presentation , 5.6 MB |
Figure S1. |
| clr14169-sup-0002-Tables.docxWord 2007 document , 32.4 KB |
Table S1. Table S2. Table S3. Table S4. Table S5. Table S6. |
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