Exhaled breath analysis during vaso-occlusive events in sickle cell disease
C. Vuong
Department of Paediatric Haematology, Emma Children's Hospital, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands
Search for more papers by this authorP. Brinkman
Department of Pulmonary Medicine, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands
Search for more papers by this authorH. Heijboer
Department of Paediatric Haematology, Emma Children's Hospital, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands
Search for more papers by this authorE. Nur
Department of Clinical Haematology, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands
Search for more papers by this authorC. L. Eckhardt
Department of Paediatric Haematology, Emma Children's Hospital, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands
Search for more papers by this authorS. W. J. Terheggen-Lagro
Department of Paediatric Pulmonology and Allergy, Emma Children's Hospital, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands
Search for more papers by this authorB. J. Biemond
Department of Clinical Haematology, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands
Search for more papers by this authorA. H. Maitland-van der Zee
Department of Pulmonary Medicine, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands
Search for more papers by this authorCorresponding Author
K. Fijnvandraat
Department of Paediatric Haematology, Emma Children's Hospital, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands
Correspondence
K. Fijnvandraat, Department of Paediatric Haematology, Emma Children's Hospital, Amsterdam University Medical Center, University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands.
Email: [email protected]
Search for more papers by this authorC. Vuong
Department of Paediatric Haematology, Emma Children's Hospital, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands
Search for more papers by this authorP. Brinkman
Department of Pulmonary Medicine, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands
Search for more papers by this authorH. Heijboer
Department of Paediatric Haematology, Emma Children's Hospital, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands
Search for more papers by this authorE. Nur
Department of Clinical Haematology, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands
Search for more papers by this authorC. L. Eckhardt
Department of Paediatric Haematology, Emma Children's Hospital, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands
Search for more papers by this authorS. W. J. Terheggen-Lagro
Department of Paediatric Pulmonology and Allergy, Emma Children's Hospital, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands
Search for more papers by this authorB. J. Biemond
Department of Clinical Haematology, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands
Search for more papers by this authorA. H. Maitland-van der Zee
Department of Pulmonary Medicine, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands
Search for more papers by this authorCorresponding Author
K. Fijnvandraat
Department of Paediatric Haematology, Emma Children's Hospital, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands
Correspondence
K. Fijnvandraat, Department of Paediatric Haematology, Emma Children's Hospital, Amsterdam University Medical Center, University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands.
Email: [email protected]
Search for more papers by this author
Open Research
DATA AVAILABILITY STATEMENT
The datasets generated and analysed during the current study are available from the corresponding author on reasonable request.
Supporting Information
| Filename | Description |
|---|---|
| bjh19942-sup-0001-Supinfo.docxWord 2007 document , 37.8 KB |
Data S1. |
| bjh19942-sup-0002-FigureS1.docxWord 2007 document , 242.8 KB |
Figure S1. |
| bjh19942-sup-0003-TableS1.docxWord 2007 document , 26.1 KB |
Table S1. |
| bjh19942-sup-0004-TableS2.docxWord 2007 document , 23.8 KB |
Table S2. |
Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
REFERENCES
- 1Esham KS, Rodday AM, Smith HP, Noubary F, Weidner RA, Buchsbaum RJ, et al. Assessment of health-related quality of life among adults hospitalized with sickle cell disease vaso-occlusive crisis. Blood Adv. 2020; 4(1): 19–27.
- 2Shirasu M, Touhara K. The scent of disease: volatile organic compounds of the human body related to disease and disorder. J Biochem. 2011; 150(3): 257–266.
- 3Miekisch W, Schubert JK, Noeldge-Schomburg GF. Diagnostic potential of breath analysis—focus on volatile organic compounds. Clin Chim Acta. 2004; 347(1–2): 25–39.
- 4Akohoue SA, Shankar S, Milne GL, Morrow J, Chen KY, Ajayi WU, et al. Energy expenditure, inflammation, and oxidative stress in steady-state adolescents with sickle cell anemia. Pediatr Res. 2007; 61(2): 233–238.
- 5Sharma A, Kumar R, Varadwaj P. Smelling the disease: diagnostic potential of breath analysis. Mol Diagn Ther. 2023; 27(3): 321–347.
- 6Kneepkens CM, Lepage G, Roy CC. The potential of the hydrocarbon breath test as a measure of lipid peroxidation. Free Radic Biol Med. 1994; 17(2): 127–160.
- 7Yin H, Xu L, Porter NA. Free radical lipid peroxidation: mechanisms and analysis. Chem Rev. 2011; 111(10): 5944–5972.
- 8Nur E, Biemond BJ, Otten HM, Brandjes DP, Schnog JJ. Oxidative stress in sickle cell disease; pathophysiology and potential implications for disease management. Am J Hematol. 2011; 86(6): 484–489.
- 9Das SK, Nair RC. Superoxide dismutase, glutathione peroxidase, catalase and lipid peroxidation of normal and sickled erythrocytes. Br J Haematol. 1980; 44(1): 87–92.
