To assess cerebral oxygenation in premature infants who are transitioning from nasal continuous positive airway pressure (nCPAP) to heated humidified high-flow nasal cannula therapy (HFNC).

Methods

A prospective observational study done in a single-centre neonatal intensive care unit (NICU). Regional cerebral oxygen saturations (RcSO₂) were measured using frequency-domain near-infrared spectroscopy (FD-NIRS) in very low birthweight (VLBW) premature infants born at <32 weeks transitioning from nCPAP to HFNC.

Results

Median gestational age was 27 weeks and median birthweight was 924 g. Recordings were performed at a median gestational age of 30 weeks and a median postnatal age of 10 days. Median weight at study entry was 1111 g. Cerebral oxygenation was not significantly different in infants transitioning from nCPAP to HFNC (66% vs 66%).

Conclusion

No difference in cerebral oxygenation in premature infants transitioning from nCPAP to HFNC was observed. This finding is reassuring and further supports the use of HFNC in preterm infants.

CONFLICT OF INTEREST

The authors have no conflicts of interest to declare.

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Volume110, Issue7

July 2021

Pages 2059-2064

Cerebral oxygenation is stable in preterm infants transitioning to heated humidified high-flow nasal cannula therapy

Abstract

Aim

Methods

Results

Conclusion

CONFLICT OF INTEREST

REFERENCES

Citing Literature

References

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Cerebral oxygenation is stable in preterm infants transitioning to heated humidified high-flow nasal cannula therapy

Abstract

Aim

Methods

Results

Conclusion

CONFLICT OF INTEREST

REFERENCES

Citing Literature

References

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