Effects of Intradialytic Neuromuscular Electrical Stimulation on Strength and Muscle Architecture in Patients With Chronic Kidney Failure: Randomized Clinical Trial
Jociane Schardong
Departamento de Fisioterapia, Programa de Pós-graduação de Ciências da Saúde de Porto Alegre, Universidade Federal de Ciências da Saúde de Porto Alegre, Rio Grande do Sul, Brazil
Search for more papers by this authorThiago Dipp
Departamento de Fisioterapia, Programa de Pós-graduação de Ciências da Saúde de Porto Alegre, Universidade Federal de Ciências da Saúde de Porto Alegre, Rio Grande do Sul, Brazil
Search for more papers by this authorCamila Bassani Bozzeto
Departamento de Fisioterapia, Programa de Pós-graduação de Ciências da Saúde de Porto Alegre, Universidade Federal de Ciências da Saúde de Porto Alegre, Rio Grande do Sul, Brazil
Search for more papers by this authorMarília Godoy da Silva
Departamento de Fisioterapia, Programa de Pós-graduação de Ciências da Saúde de Porto Alegre, Universidade Federal de Ciências da Saúde de Porto Alegre, Rio Grande do Sul, Brazil
Search for more papers by this authorGabriela Leivas Baldissera
Departamento de Fisioterapia, Programa de Pós-graduação de Ciências da Saúde de Porto Alegre, Universidade Federal de Ciências da Saúde de Porto Alegre, Rio Grande do Sul, Brazil
Search for more papers by this authorRaíssa de Castro Ribeiro
Departamento de Fisioterapia, Programa de Pós-graduação de Ciências da Saúde de Porto Alegre, Universidade Federal de Ciências da Saúde de Porto Alegre, Rio Grande do Sul, Brazil
Search for more papers by this authorBruna Pan Valdemarca
Departamento de Fisioterapia, Programa de Pós-graduação de Ciências da Saúde de Porto Alegre, Universidade Federal de Ciências da Saúde de Porto Alegre, Rio Grande do Sul, Brazil
Search for more papers by this authorAlexandre Severo do Pinho
Departamento de Fisioterapia, Programa de Pós-graduação de Ciências da Saúde de Porto Alegre, Universidade Federal de Ciências da Saúde de Porto Alegre, Rio Grande do Sul, Brazil
Search for more papers by this authorGraciele Sbruzzi
Departamento de Fisioterapia, Programa de Pós-graduação em Ciências do Movimento, Universidade Federal do Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil
Search for more papers by this authorCorresponding Author
Rodrigo Della Méa Plentz
Departamento de Fisioterapia, Programa de Pós-graduação de Ciências da Saúde de Porto Alegre, Universidade Federal de Ciências da Saúde de Porto Alegre, Rio Grande do Sul, Brazil
Address correspondence and reprint requests to Rodrigo Della Méa Plentz, Universidade Federal de Ciências da Saúde de Porto Alegre (UFCSPA), Sarmento Leite, 245, Porto Alegre, Rio Grande do Sul, Brazil, 90050-170. E-mail: [email protected]Search for more papers by this authorJociane Schardong
Departamento de Fisioterapia, Programa de Pós-graduação de Ciências da Saúde de Porto Alegre, Universidade Federal de Ciências da Saúde de Porto Alegre, Rio Grande do Sul, Brazil
Search for more papers by this authorThiago Dipp
Departamento de Fisioterapia, Programa de Pós-graduação de Ciências da Saúde de Porto Alegre, Universidade Federal de Ciências da Saúde de Porto Alegre, Rio Grande do Sul, Brazil
Search for more papers by this authorCamila Bassani Bozzeto
Departamento de Fisioterapia, Programa de Pós-graduação de Ciências da Saúde de Porto Alegre, Universidade Federal de Ciências da Saúde de Porto Alegre, Rio Grande do Sul, Brazil
Search for more papers by this authorMarília Godoy da Silva
Departamento de Fisioterapia, Programa de Pós-graduação de Ciências da Saúde de Porto Alegre, Universidade Federal de Ciências da Saúde de Porto Alegre, Rio Grande do Sul, Brazil
Search for more papers by this authorGabriela Leivas Baldissera
Departamento de Fisioterapia, Programa de Pós-graduação de Ciências da Saúde de Porto Alegre, Universidade Federal de Ciências da Saúde de Porto Alegre, Rio Grande do Sul, Brazil
Search for more papers by this authorRaíssa de Castro Ribeiro
Departamento de Fisioterapia, Programa de Pós-graduação de Ciências da Saúde de Porto Alegre, Universidade Federal de Ciências da Saúde de Porto Alegre, Rio Grande do Sul, Brazil
Search for more papers by this authorBruna Pan Valdemarca
Departamento de Fisioterapia, Programa de Pós-graduação de Ciências da Saúde de Porto Alegre, Universidade Federal de Ciências da Saúde de Porto Alegre, Rio Grande do Sul, Brazil
Search for more papers by this authorAlexandre Severo do Pinho
Departamento de Fisioterapia, Programa de Pós-graduação de Ciências da Saúde de Porto Alegre, Universidade Federal de Ciências da Saúde de Porto Alegre, Rio Grande do Sul, Brazil
Search for more papers by this authorGraciele Sbruzzi
Departamento de Fisioterapia, Programa de Pós-graduação em Ciências do Movimento, Universidade Federal do Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil
Search for more papers by this authorCorresponding Author
Rodrigo Della Méa Plentz
Departamento de Fisioterapia, Programa de Pós-graduação de Ciências da Saúde de Porto Alegre, Universidade Federal de Ciências da Saúde de Porto Alegre, Rio Grande do Sul, Brazil
Address correspondence and reprint requests to Rodrigo Della Méa Plentz, Universidade Federal de Ciências da Saúde de Porto Alegre (UFCSPA), Sarmento Leite, 245, Porto Alegre, Rio Grande do Sul, Brazil, 90050-170. E-mail: [email protected]Search for more papers by this authorAbstract
This study aimed to evaluate the effects of neuromuscular electrical stimulation (NMES) on muscle strength and architecture, functional capacity, and endothelial function in patients with chronic kidney failure (CKF) on hemodialysis (HD). Twenty-one patients with CKF on HD were randomized into a control group (CG; n = 10) and neuromuscular electrical stimulation group (NMESG; n = 11) who received NMES in the quadriceps muscle for 8 weeks, 3 times/week (20–34 min) during HD sessions. The muscle strength of the lower limbs was evaluated by dynamometry and sit-and-stand test (SST); muscle architecture through ultrasonography; functional capacity by the distance covered in a 6-min walk test and the endothelial function by flow-mediated dilatation technique of the brachial artery. There was an increase in the strength of the lower limbs in the NMESG compared to the CG (dynamometry: 43.28 ± 16.94 vs. 35.84 ± 16.89, P = 0.006; SST: 16.10 ± 6.51 vs. 12.50 ± 4.7, P = 0.029). There was a significant reduction in pennation angles of the right vastus lateralis (RVL) and left vastus lateralis (LVL) in the CG when compared to the NMESG (RVL: 11.93 [10.70–15.11] vs. 13.57 [11.81–15.96], P = 0.039; LVL: 11.62 [9.00–14.20] vs. 15.52 [12.86–20.02], P = 0.042). There was no change in functional capacity and in the endothelial function for CG and NMESG, respectively. In conclusion, NMES increases muscle strength and has a protective effect against muscle atrophy of the lower limbs of patients with chronic kidney failure on HD.
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