Brief Report
Erythema papulatum centrifugum and new diagnostic criteria
Li-wen Zhang and Wen-ju Wang contributed equally to this work.
Li-wen Zhang, MD. Wen-ju Wang, MD. Cun-huo Jiang, MD. Yong-hong Lu, MD. Cong-hui Li, PhD. Lin Li, MD. Li-xin Fu, MD. Jia-yi Li, MD. Tao Chen, PhD. Fen Li, MD.
Funding: This article has no funding source.
Conflict of interest: The authors have no conflict of interest to declare.
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Abstract
Erythema papulatum centrifugum (EPC), also known as erythema papulosa semicircularis recidivans (EPSR), is distinct from eczema and other well-described figurate erythemas characterised by annular erythematous lesions. We report 7 cases of EPC and propose new diagnostic criteria including the following: (i) EPC is characterised by single or multiple recurrent expanding annular or semi annular erythema with central regression, surrounded by tiny red papules; (ii) the lesions regularly relapse and resolve; (iii) the histopathologic feature shows superficial perivascular inflammation with or without mild inflammation around sweat glands in the mid dermis and (iv) patients lack other associated cutaneous or internal abnormalities.
