The relationship between changes in peritoneal membrane solute transfer characteristics and cardiac remodeling in patients with peritoneal dialysis
Corresponding Author
Mehmet Ası Oktan
Dokuz Eylul University Faculty of Medicine, Department of Internal Medicine, Division of Nephrology, Izmir, Turkey
Correspondence
Mehmet Ası Oktan, Dokuz Eylul University Hospital, Department of Nephrology, 35330, Balcova-Izmir, Turkey.
Email: [email protected]
Search for more papers by this authorBerfu Korucu
Dokuz Eylul University Faculty of Medicine, Department of Internal Medicine, Division of Nephrology, Izmir, Turkey
Search for more papers by this authorAyşe Çolak
Department of Cardiology, Dokuz Eylül University School of Medicine, Izmir, Turkey
Search for more papers by this authorYelda Deligöz Bildacı
Dokuz Eylul University Faculty of Medicine, Department of Internal Medicine, Division of Nephrology, Izmir, Turkey
Search for more papers by this authorCaner Çavdar
Dokuz Eylul University Faculty of Medicine, Department of Internal Medicine, Division of Nephrology, Izmir, Turkey
Search for more papers by this authorSerpil Müge Değer
Dokuz Eylul University Faculty of Medicine, Department of Internal Medicine, Division of Nephrology, Izmir, Turkey
Search for more papers by this authorCorresponding Author
Mehmet Ası Oktan
Dokuz Eylul University Faculty of Medicine, Department of Internal Medicine, Division of Nephrology, Izmir, Turkey
Correspondence
Mehmet Ası Oktan, Dokuz Eylul University Hospital, Department of Nephrology, 35330, Balcova-Izmir, Turkey.
Email: [email protected]
Search for more papers by this authorBerfu Korucu
Dokuz Eylul University Faculty of Medicine, Department of Internal Medicine, Division of Nephrology, Izmir, Turkey
Search for more papers by this authorAyşe Çolak
Department of Cardiology, Dokuz Eylül University School of Medicine, Izmir, Turkey
Search for more papers by this authorYelda Deligöz Bildacı
Dokuz Eylul University Faculty of Medicine, Department of Internal Medicine, Division of Nephrology, Izmir, Turkey
Search for more papers by this authorCaner Çavdar
Dokuz Eylul University Faculty of Medicine, Department of Internal Medicine, Division of Nephrology, Izmir, Turkey
Search for more papers by this authorSerpil Müge Değer
Dokuz Eylul University Faculty of Medicine, Department of Internal Medicine, Division of Nephrology, Izmir, Turkey
Search for more papers by this authorAbstract
Introduction
We aimed to determine the relationship between the dilatation of the heart chambers and the change in peritoneal membrane solute transfer characteristics (PMTC) in long-term peritoneal dialysis (PD) patients.
Methods
This is a retrospective, single-center study including the follow-up of maintenance PD patients. According to the changes in PMTC from baseline to the last visit, patients were divided into three groups; stable (n = 11), increased (n = 41), and decreased transporters (n = 35).
Results
Left atrium (LA) and Right ventricle (RV) dilatation were more prominent in the PMTC-decreased group compared to PMTC-increased and stable groups (p < 0.001 and p = 0.07, respectively). The Cox regression analysis showed that only decreased PMTC was associated with LA dilatation (HR 2.89 [CI 95%1.54, 5.45] p < 0.01) and RV dilatation (HR 3.01 [CI 95%1.40, 6.21] p < 0.01).
Conclusion
PD can be associated with unfavorable dynamic changes in cardiac structure and functions even at the subclinical level.
CONFLICT OF INTEREST STATEMENT
The authors declare no conflicts of interest.
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