ORIGINAL ARTICLE
The effect of nonpharmacologic interventions for muscle cramps and restless-leg syndrome in hemodialysis patients: A meta-analysis of randomized controlled trials
Gulsah Kesik,
Nese Altinok Ersoy,
Corresponding Author
Gulsah Kesik
Internal Medicine Nursing Department, Faculty of Nursing, Hacettepe University, Ankara, Turkey
Correspondence
Gulsah Kesik, Internal Medicine Nursing Department, Faculty of Nursing, Hacettepe University, Ankara, Turkey.
Email: [email protected]
Search for more papers by this authorNese Altinok Ersoy
Internal Medicine Nursing Department, Faculty of Nursing, Hacettepe University, Ankara, Turkey
Search for more papers by this authorGulsah Kesik,
Nese Altinok Ersoy,
Corresponding Author
Gulsah Kesik
Internal Medicine Nursing Department, Faculty of Nursing, Hacettepe University, Ankara, Turkey
Correspondence
Gulsah Kesik, Internal Medicine Nursing Department, Faculty of Nursing, Hacettepe University, Ankara, Turkey.
Email: [email protected]
Search for more papers by this authorNese Altinok Ersoy
Internal Medicine Nursing Department, Faculty of Nursing, Hacettepe University, Ankara, Turkey
Search for more papers by this authorPROSPERO registration no: CRD42022334683.
Abstract
Introduction
We performed a meta-analysis to evaluate the effect of the nonpharmacologic interventions on muscle related symptoms including cramping and restless leg syndrome in hemodialysis patients.
Methods
Articles published between 2002 and 2022 were searched in six databases. The standardized mean differences were determined by the upper and lower limits of 95% confidence intervals. Publication bias was assessed by conducting the Egger test and examined visually using a funnel plot.
Results
Fourteen studies were included in this meta-analysis. The types of interventions included exercise (n = 5), aromatherapy (n = 5), reflexology (n = 3), massage (n = 1), and acupressure (n = 1). The methodological quality assessment revealed 13 studies were strong quality, while only one study was moderate quality. The Egger test indicated no significant publication biases.
Conclusion
Healthcare professionals can use non-pharmacological methods to manage muscle-related symptoms because of not only beneficial effects but also it is practical, well-tolerated, easy integrated into the treatment and care.
CONFLICT OF INTEREST STATEMENT
The authors declare no conflicts of interest.
Supporting Information
| Filename | Description |
|---|---|
| tap13968-sup-0001-Supplementary_material_1.docxWord 2007 document , 19.1 KB | Supplementary material 1. Search strategy for each database. |
Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
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