REVIEW
Therapeutic plasma exchange in anti-N-methyl-D-aspartate receptor encephalitis
Yuan Zhang,
Yong-kang Cheng,
Chun-feng Yang,
Lin-mei Jin,
Yu-mei Li,
Yuan Zhang
Department of Pediatric Intensive Care Unit, The First Hospital of Jilin University, Jilin, China
Search for more papers by this authorYong-kang Cheng
Department of Pediatric Intensive Care Unit, The First Hospital of Jilin University, Jilin, China
Search for more papers by this authorChun-feng Yang
Department of Pediatric Intensive Care Unit, The First Hospital of Jilin University, Jilin, China
Search for more papers by this authorLin-mei Jin
Department of Pediatric Intensive Care Unit, The First Hospital of Jilin University, Jilin, China
Search for more papers by this authorCorresponding Author
Yu-mei Li
Department of Pediatric Intensive Care Unit, The First Hospital of Jilin University, Jilin, China
Correspondence
Yu-mei Li, Department of Pediatric Intensive Care Unit, The First Hospital of Jilin University, No. 1 Xinmin Street, Changchun 130021, Jilin, China.
Email: [email protected]
Search for more papers by this authorYuan Zhang,
Yong-kang Cheng,
Chun-feng Yang,
Lin-mei Jin,
Yu-mei Li,
Yuan Zhang
Department of Pediatric Intensive Care Unit, The First Hospital of Jilin University, Jilin, China
Search for more papers by this authorYong-kang Cheng
Department of Pediatric Intensive Care Unit, The First Hospital of Jilin University, Jilin, China
Search for more papers by this authorChun-feng Yang
Department of Pediatric Intensive Care Unit, The First Hospital of Jilin University, Jilin, China
Search for more papers by this authorLin-mei Jin
Department of Pediatric Intensive Care Unit, The First Hospital of Jilin University, Jilin, China
Search for more papers by this authorCorresponding Author
Yu-mei Li
Department of Pediatric Intensive Care Unit, The First Hospital of Jilin University, Jilin, China
Correspondence
Yu-mei Li, Department of Pediatric Intensive Care Unit, The First Hospital of Jilin University, No. 1 Xinmin Street, Changchun 130021, Jilin, China.
Email: [email protected]
Search for more papers by this authorFirst published: 27 September 2022
Yuan Zhang and Yong-kang Cheng contributed to the work equally and should be regarded as co-first authors
Funding information: Jilin Provincial Department of science and technology, Grant/Award Number: 20210204134YY
Abstract
Anti-N-methyl-D-aspartate receptor (anti-NMDAR) encephalitis is the most commonly identified cause of autoimmune encephalitis. Therapeutic plasma exchange has been increasingly employed to treat this disease. This expansion is a consequence of improved techniques and apheresis instruments, as well as the recognition of its applicability in neurological diseases. However, several aspects of treatment remain incompletely clarified, and treatment strategies are still heterogeneous, especially with regard to therapeutic plasma exchange in anti-NMDAR encephalitis. This review provides an overview of the use of therapeutic plasma exchange including the principle and mechanisms, the evidence, initial time, efficiency and complications in anti-NMDAR encephalitis.
CONFLICT OF INTEREST
There are no financial and other conflicts of interest to disclose.
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