Volume 63, Issue 5 pp. 1568-1572
Case Report

An Unusual Cause of Headache and Sudden Death of a Young Sailor—Postmortem Computed Tomography and Histological Findings of a Fatal Retroperitoneal Malignant Mixed Germ Cell Tumor

Belinda Lee M.B.B.S., F.R.C.Path.

Corresponding Author

Belinda Lee M.B.B.S., F.R.C.Path.

Forensic Medicine Division, Health Sciences Authority, 11 Outram Rd, Singapore, 169078 Singapore

Additional information and reprint requests:

Belinda Lee, M.B.B.S., F.R.C.Path.

Forensic Medicine Division

Health Sciences Authority

11 Outram Rd

Singapore 169078

Singapore

E-mail: [email protected]

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Michelle Chan M.B.B.S., F.R.C.Path.

Michelle Chan M.B.B.S., F.R.C.Path.

Department of Anatomical Pathology, Singapore General Hospital, Outram Road, Singapore, 169856 Singapore

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Ronald Goh M.B.B.S., F.R.C.P.A.

Ronald Goh M.B.B.S., F.R.C.P.A.

Department of Anatomical Pathology, Singapore General Hospital, Outram Road, Singapore, 169856 Singapore

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First published: 22 November 2017
Citations: 2

Abstract

A 26-year-old Caucasian sailor, with no past medical history aside from headache for the last 1 week, was found dead in his cabin. The body was stored in a refrigerator on board and disembarked for autopsy 3 days later. Autopsy showed a large, nodular, necrotic and hemorrhagic retroperitoneal mass, and smaller hemorrhagic nodules in the brain, lungs, liver, and left kidney, with the brain being markedly edematous. Both testes were descended and normal. Histologically, the retroperitoneal mass showed a malignant mixed germ cell tumor comprising choriocarcinoma, embryonal carcinoma, and teratoma components. Retroperitoneal extragonadal germ cell tumors are uncommon, and this case of a young male who presented with headache and sudden death due to metastases is extremely rare.

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