Volume 50, Issue 8 pp. 1076-1080
CONCISE COMMUNICATION

Palmoplantar pustulosis and pustulotic arthro-osteitis associated with multiple venous occlusion: A case report and literature review

Emi Inoue

Corresponding Author

Emi Inoue

Department of Dermatology, Nippon Life Hospital, Osaka, Japan

Correspondence

Emi Inoue, Department of Dermatology, Nippon Life Hospital, 2-1-54 Enokojima, Nishi-ku, Osaka-shi, Osaka 550-0006, Japan.

Email: [email protected]

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Shiori Hiroumi

Shiori Hiroumi

Department of Respiratory Medicine and Clinical Immunology, Nippon Life Hospital, Osaka, Japan

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Sachina Sato

Sachina Sato

Department of Dermatology, Nippon Life Hospital, Osaka, Japan

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Misa Hayashi

Misa Hayashi

Department of Dermatology, Nippon Life Hospital, Osaka, Japan

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Hachiro Konaka

Hachiro Konaka

Department of Respiratory Medicine and Clinical Immunology, Nippon Life Hospital, Osaka, Japan

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Shigeyoshi Tsuji

Shigeyoshi Tsuji

Department of Orthopeadic Surgery, Nippon Life Hospital, Osaka, Japan

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Mari Higashiyama

Mari Higashiyama

Department of Dermatology, Nippon Life Hospital, Osaka, Japan

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First published: 05 April 2023

Abstract

Pustulotic arthro-osteitis (PAO) is a rare chronic inflammatory arthropathy associated with palmoplantar pustulosis. The pathogenesis of PAO remains unclear. The most common musculoskeletal involvement in PAO is ossification of the sternoclavicular joints. A combination of parietal inflammation and hyperostosis-induced mechanical compression in this region is hypothesized to contribute to multiple venous thrombosis. Here, we present a 66-year-old man with PAO-associated multiple venous occlusion who was successfully treated with guselkumab. We also discuss its clinical manifestation and cause by reviewing the literature.

CONFLICT OF INTEREST STATEMENT

None declared.

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