(+)-N-{4-[(1S,2S)-2-(Dimethylamino)-1-(1H-imidazol-1-yl)propyl]phenyl}-2-benzothiazolamine
First published: 03 August 2004
Oswald M. Peeters, e-mail: [email protected]
Abstract
The metabolism of all-trans-retinoic acid is mediated by a cytochrome dependent P-450 system. The title compound, C21H23N5S, is an inhibitor of the P-450 system. Two planar rings connected via a central CH group form a dihedral angle of 80.2 (1)°; the planar systems connected through an NH group form a dihedral angle of 37.12 (8)°. The N—H⋯N hydrogen bonds link the molecules of the title compound into infinite chains stretching along the c direction.
