Volume 56, Issue 1 pp. 116-117

5-Ethyl-2′-deoxy-4′-thiouridine (R)-S-oxide monohydrate

Ming Sun

Ming Sun

School of Chemistry, University of Birmingham, Birmingham B15 2TT, England

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Alasdair C. Macculloch

Alasdair C. Macculloch

School of Chemistry, University of Birmingham, Birmingham B15 2TT, England

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Thomas A. Hamor

Thomas A. Hamor

School of Chemistry, University of Birmingham, Birmingham B15 2TT, England

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Richard T. Walker

Richard T. Walker

School of Chemistry, University of Birmingham, Birmingham B15 2TT, England

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First published: 01 July 2004
Thomas A. Hamor, e-mail: [email protected]

Abstract

The pyrimidine ring of the title compound, C11H16N2O5S·H2O, is planar to within 0.026 (1) Å and makes an angle of 77.73 (8)° with the mean plane of the thiosugar ring. In terms of standard nucleoside nomenclature, this ring has a C1′-exo,C2′-endo conformation. The O5′—C5′—C4′—C3′ torsion angle is −167.4 (2)° and the glycosidic S4′—C1′—N1—C2 torsion angle is −101.8 (2)° (anti).

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