Value of regional lymphadenectomy in pancreatic cancer
C. BASSI,
R. SALVIA,
G. BUTTURINI,
S. MARCUCCI,
G. BARUGOLA,
M. FALCONI,
Corresponding Author
C. BASSI
Surgical and Gastroenterological Department, University of Verona, Verona, Italy
C. Bassi, Università di Verona, Policlinico Borgo Roma ‘G.B. Rossi’, 37134, Verona, Italy. Tel: +390458074553/2. Fax: +390458074662 E-mail: [email protected]Search for more papers by this authorR. SALVIA
Surgical and Gastroenterological Department, University of Verona, Verona, Italy
Search for more papers by this authorG. BUTTURINI
Surgical and Gastroenterological Department, University of Verona, Verona, Italy
Search for more papers by this authorS. MARCUCCI
Surgical and Gastroenterological Department, University of Verona, Verona, Italy
Search for more papers by this authorG. BARUGOLA
Surgical and Gastroenterological Department, University of Verona, Verona, Italy
Search for more papers by this authorM. FALCONI
Surgical and Gastroenterological Department, University of Verona, Verona, Italy
Search for more papers by this authorC. BASSI,
R. SALVIA,
G. BUTTURINI,
S. MARCUCCI,
G. BARUGOLA,
M. FALCONI,
Corresponding Author
C. BASSI
Surgical and Gastroenterological Department, University of Verona, Verona, Italy
C. Bassi, Università di Verona, Policlinico Borgo Roma ‘G.B. Rossi’, 37134, Verona, Italy. Tel: +390458074553/2. Fax: +390458074662 E-mail: [email protected]Search for more papers by this authorR. SALVIA
Surgical and Gastroenterological Department, University of Verona, Verona, Italy
Search for more papers by this authorG. BUTTURINI
Surgical and Gastroenterological Department, University of Verona, Verona, Italy
Search for more papers by this authorS. MARCUCCI
Surgical and Gastroenterological Department, University of Verona, Verona, Italy
Search for more papers by this authorG. BARUGOLA
Surgical and Gastroenterological Department, University of Verona, Verona, Italy
Search for more papers by this authorM. FALCONI
Surgical and Gastroenterological Department, University of Verona, Verona, Italy
Search for more papers by this authorAbstract
Radical surgical resection and adjuvant chemotherapy are the goal standard to attempt significant long term survival in patients suffering from ductal pancreatic cancer. The role of extended lymph-node dissection is still a debated issue. In this paper a deep review of the experiences reported in the literature is carried out. Several studies are limited, not randomized and retrospective: generally speaking they seem to suggest a positive role in node dissection. Unfortunately, this trend is not confirmed in the only two trials conducted in a prospective and randomized setting. Moreover the results of these studies are also difficult to compare. At the moment we can say that extended lymphadenectomy does not play a determinant role for long term survival but a positive trend has been shown for node positive patients.
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