Volume 27, Issue 1 pp. 35-36

Rare polymorphisms in the promoter regions of the human interleukin-12 p35 and interleukin-12 p40 subunit genes

Vera Pravica

Corresponding Author

Vera Pravica

Immunology Research Group, School of Biological Sciences, University of Manchester, Oxford Road, Manchester M13 9PT, UK

Dr Vera Pravica, Immunology Research Group, School of Biological Sciences, University of Manchester, Stopford Building 3.239, Oxford Road, Manchester M13 9PT, UK.Search for more papers by this author
Iain J. Brogan

Iain J. Brogan

Immunology Research Group, School of Biological Sciences, University of Manchester, Oxford Road, Manchester M13 9PT, UK

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Ian V. Hutchinson

Ian V. Hutchinson

Immunology Research Group, School of Biological Sciences, University of Manchester, Oxford Road, Manchester M13 9PT, UK

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First published: 25 December 2001
Citations: 14

Abstract

We have described two rare, single-nucleotide polymorphisms within the promoter regions of the IL-12 p35 and p40 subunit genes. Transitions C to T at position −916 from the transcription start of the IL-12 p35 gene and G to T at position −1287 in the IL-12 p40 gene were observed.

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