Systemic involvement in scleredema of Buschke associated with IgG-kappa paraproteinaemia
Corresponding Author
T. BASARAB
Department of Dermatology, Ealing Hospital, Southall, Middlesex, U.K.
T.Basarab, Ealing Hospital, Uxbridge Road, Southall, Middlesex UB1 3HW, U.K.Search for more papers by this authorN.P. BURROWS
Department of Dermatology, Addenbrook's Hospital, Cambridge, UK
Search for more papers by this authorS.E MUNN
Department of Dermatology, Ealing Hospital, Southall, Middlesex, U.K.
Search for more papers by this authorR.RUSSELL JONES
Department of Dermatology, Ealing Hospital, Southall, Middlesex, U.K.
Search for more papers by this authorCorresponding Author
T. BASARAB
Department of Dermatology, Ealing Hospital, Southall, Middlesex, U.K.
T.Basarab, Ealing Hospital, Uxbridge Road, Southall, Middlesex UB1 3HW, U.K.Search for more papers by this authorN.P. BURROWS
Department of Dermatology, Addenbrook's Hospital, Cambridge, UK
Search for more papers by this authorS.E MUNN
Department of Dermatology, Ealing Hospital, Southall, Middlesex, U.K.
Search for more papers by this authorR.RUSSELL JONES
Department of Dermatology, Ealing Hospital, Southall, Middlesex, U.K.
Search for more papers by this authorSummary
Scleredema is a rare primary cutaneous mucinosis. Systemic involvement is uncommon and histological confirmation is often lacking. We report a case of a 60-year-old man with scleredema and evidence of mucin deposition on biopsies from multiple extracutaneous sites. The bone marrow, nerve, hepatic and salivary gland involvement seen on histology in our patient has not, to our knowledge, been previously reported in this condition.
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