Incidence of chronic myeloproliferative disorders in the city of Göteborg, Sweden 1983–1992

Abstract: An estimation of the incidence of polycythaemia vera (PV), essential thrombocythaemia (ET) and chronic idiopathic myelofibrosis (CIM) in the city of Göteborg, Sweden during the period 1983–1992 was made from a retrospective case analysis of patients registered as chronic myeloproliferative disorders (CMPD) at the Departments of Medicine and the Department of Pathology of the two major hospitals in the city. A total of 125 cases of PV, 56 males and 69 females were identified. The number of cases as well as the age-specific incidence increased with age. The over all annual gender-specific incidence was 2.69 cases per 10⁵ male inhabitants and 3.12 cases per 10⁵ female inhabitants. The incidence of PV in relation to the European Standard Population was 2.02 cases per 10⁵ inhabitants and year. There were 72 cases, 20 males and 52 females, with ET. The age-specific incidence was in all ages higher for females than for males and increased with age. The annual gender-specific incidence was 0.96 per 10⁵ male inhabitants and 2.35 per 10⁵ female inhabitants. The incidence of ET in relation to the European Standard Population was 1.28 per 10⁵ persons and year. There were 20 cases of CIM, 11 males and 9 females. The annual gender-specific incidence of CIM was 0.53/10⁵ male inhabitants and 0.41/10⁵ female inhabitants. The incidence of CIM in relation to the European Standard Population was 0.31 per 10⁵ persons and year. Seven persons, 2 males and 5 females, had a CMPD that could not be included in any of the above-mentioned groups, but were registered as CMPD, unclassified.