Three newly identified HLA-B alleles: B*5124, B*5306, B*5307 and confirmation of B*0809 and B*5606
The names B*5124, B*5306, B*5307 have been officially assigned by the WHO Nomenclature Committee. This follows the agreed policy that, subject to the conditions stated in the most recent nomenclature report ( 1), names will be assigned to new sequences as they are identified. Lists of such new names will be published in the following WHO nomenclature report. The sequences reported in this paper have been submitted to the EMBL nucleotide sequence database in Heidelberg and have been assigned the following accession numbers: B*0809: AJ276994, B*5124: AJ276995, B*5306: AJ276996, B*5307: AJ293856AJ293857, B*5606: AJ276993.
Abstract
Abstract: Five HLA-B sequences are described which have been detected as irregular patterns during routine molecular typing. Sequencing of HLA-B exon 2 and 3, both heterozygous and after group specific amplification, revealed three new HLA-B alleles: B*5124, B*5306 and B*5307, whereas the sequences of B*0809 and B*5606 were confirmed. Serological typing showed that B*0809 is expressed as a regular B8, B*5124 as a regular B51, B*5306 as a B51/B53-like variant and B*5606 as a B‘blank’-Bw61.
