Volume 56, Issue 6 pp. 560-562

Two new HLA DPB1 alleles identified by sequence-based typing: DPB1*8201 and DPB1*8301

C.E.M. Voorter

C.E.M. Voorter

Tissue Typing Laboratory, University Hospital Maastricht, Maastricht, The Netherlands

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M.G.J. Tilanus

M.G.J. Tilanus

Department of Pathology, Section Molecular Pathology, University Hospital Utrecht, Utrecht, The Netherlands

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E.M. Van Den Berg-Loonen

E.M. Van Den Berg-Loonen

Tissue Typing Laboratory, University Hospital Maastricht, Maastricht, The Netherlands

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First published: 25 December 2001
Citations: 9
Correspondence to:Ella M. van den Berg-Loonen
Tissue Typing Laboratory
University Hospital Maastricht
P.O. Box 5800
6202 AZ Maastricht
The Netherlands
Tel: +31 43 387 4680
Fax: +31 43 387 4678

The nucleotide sequence data reported in this paper will appear in the EMBL Nucleotide Sequence Database with the accession numbers Y18499 (DPB1*8201) and AJ2380050 (DPB1*8301). The names DPB1*8201 and *8301 have been officially assigned by the WHO Nomenclature Committee in January 1999 and May 1999. This follows the agreed policy that, subject to conditions stated in the most recent Nomenclature Report ( 8), names will be assigned to new sequences as they are identified. Lists of such new names will be published in the following WHO Nomenclature Report.

Abstract:

Two new HLA DPB1 alleles were identified by sequence-based typing and are reported. Both alleles differ from DPB1*0402 by a single nucleotide: DPB1*8201 has a difference at position 359 (codon 91) leading to an amino acid change from arg to his, making this position a new polymorphic site; DPB1*8301 has a difference at position 280 (codon 65) changing the amino acid from ile to phe ( ).

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