REVIEW ARTICLE

Efficiency and clinical outcomes of Moses technology for holmium laser enucleation of the prostate: An evidence-based analysis

Kangsen Li MM

Department of Urology, Nanchong Central Hospital, The Second Clinical Medical College, North Sichuan Medical College (University), Nanchong, China

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Chunyang Meng MM,

Chunyang Meng MM

Department of Urology, Nanchong Central Hospital, The Second Clinical Medical College, North Sichuan Medical College (University), Nanchong, China

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Jinze Li MD,

Jinze Li MD

Department of Urology, Institute of Urology, West China Hospital, Sichuan University, Chengdu, China

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Lijian Gan MM,

Lijian Gan MM

Department of Urology, Nanchong Central Hospital, The Second Clinical Medical College, North Sichuan Medical College (University), Nanchong, China

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Lei Peng MD,

Lei Peng MD

Department of Urology, The Second Hospital of Lanzhou University Medical School, Lanzhou, China

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Yunxiang Li MD,

Corresponding Author

Yunxiang Li MD

[email protected]

orcid.org/0000-0002-8010-3610

Department of Urology, Nanchong Central Hospital, The Second Clinical Medical College, North Sichuan Medical College (University), Nanchong, China

Correspondence Yunxiang Li, Department of Urology, Nanchong Central Hospital, The Second Clinical Medical College, North Sichuan Medical College (University), Nanchong, Sichuan 637000, China.

Email: [email protected]

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Ji Wu MM,

Ji Wu MM

Department of Urology, Nanchong Central Hospital, The Second Clinical Medical College, North Sichuan Medical College (University), Nanchong, China

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Kangsen Li MM,

Kangsen Li MM

Department of Urology, Nanchong Central Hospital, The Second Clinical Medical College, North Sichuan Medical College (University), Nanchong, China

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Chunyang Meng MM,

Chunyang Meng MM

Department of Urology, Nanchong Central Hospital, The Second Clinical Medical College, North Sichuan Medical College (University), Nanchong, China

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Jinze Li MD,

Jinze Li MD

Department of Urology, Institute of Urology, West China Hospital, Sichuan University, Chengdu, China

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Lijian Gan MM,

Lijian Gan MM

Department of Urology, Nanchong Central Hospital, The Second Clinical Medical College, North Sichuan Medical College (University), Nanchong, China

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Lei Peng MD,

Lei Peng MD

Department of Urology, The Second Hospital of Lanzhou University Medical School, Lanzhou, China

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Yunxiang Li MD,

Corresponding Author

Yunxiang Li MD

[email protected]

orcid.org/0000-0002-8010-3610

Department of Urology, Nanchong Central Hospital, The Second Clinical Medical College, North Sichuan Medical College (University), Nanchong, China

Correspondence Yunxiang Li, Department of Urology, Nanchong Central Hospital, The Second Clinical Medical College, North Sichuan Medical College (University), Nanchong, Sichuan 637000, China.

Email: [email protected]

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Ji Wu MM,

Ji Wu MM

Department of Urology, Nanchong Central Hospital, The Second Clinical Medical College, North Sichuan Medical College (University), Nanchong, China

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First published: 21 September 2022

https://doi.org/10.1002/pros.24438

These authors contributed equally to this study.

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Abstract

Background

To compare the safety and clinical efficacy of Moses laser enucleation of the prostate (MoLEP) with those of holmium laser enucleation of the prostate (HoLEP) for treating benign prostatic hyperplasia (BPH).

Methods

We systematically searched PubMed, Embase, Web of Science, China National Knowledge Infrastructure (CNKI), Wanfang databases, and SinoMed databases. The retrieval period was from the establishment of the database to March 2022. Stata17.0 was used for calculations and statistical analyses.

Results

This study included 12 articles comprising 1160 patients for meta-analysis. Compared with those of the HoLEP group, the hemostasis time (weighted mean difference [WMD] = −4.66, 95% confidence interval [CI] [−6.47, −2.84], p < 0.001), enucleation time (WMD = −7.23, 95% CI [−10.67, −3.79], p < 0.001), operative time (WMD = −15.02, 95% CI [−20.50, −9.53], p< 0.001), length of hospital stay (WMD = −15.02, 95% CI [−20.50, −9.53], p< 0.001), intraoperative blood loss (WMD = −11.19, 95% CI [−12.94, −9.44], p< 0.001), and total postoperative complications rate (OR = 0.51, 95% CI [0.32, 0.81], p = 0.004) were shorter in the MoLEP group. Postoperative quality of life (WMD = 0.30, 95% CI [0.00, 0.59], p = 0.047) was lower in the HoLEP group, and there were no statistically significant differences in the International Prostate Symptom Score, postoperative maximum urinary flow rate, and postoperative residual urine (p > 0.05).

Conclusion

MoLEP has more advantages than HoLEP in terms of safety, shorter operation time and hospital stay, and fewer complications. However, this conclusion needs to be verified with a larger sample size, longer follow-up time, and multicenter randomized controlled trial data.

CONFLICT OF INTEREST

The authors declare no conflict of interest.

Open Research

DATA AVAILABILITY STATEMENT

All data generated and analyzed during this study are included in this published article.

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Volume83, Issue1

January 1, 2023

Pages 3-15

Efficiency and clinical outcomes of Moses technology for holmium laser enucleation of the prostate: An evidence-based analysis

Abstract

Background

Methods

Results

Conclusion

CONFLICT OF INTEREST

Open Research

DATA AVAILABILITY STATEMENT

REFERENCES

References

Information

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Efficiency and clinical outcomes of Moses technology for holmium laser enucleation of the prostate: An evidence-based analysis

Abstract

Background

Methods

Results

Conclusion

CONFLICT OF INTEREST

Open Research

DATA AVAILABILITY STATEMENT

REFERENCES

References

Related

Information