Cover Image

Conformational landscape of the 4-helix bundle HAMP signaling domain family represented by AlphaFold2 models. Each point represents a single model of a HAMP domain, with their relative positions reflecting structural similarity. The conformational landscape shows four basic motions that the HAMP domains can undergo and is colored according to each of these motions. For details, see: Aleksander Winski et al., Protein Science, 2023. https://doi.org/10.1002/pro.4846