Conjugated polymers containing the triphenylamine group have been synthesized and used to prepare conjugated polymer nanoparticles (CPNs). Described on page 1898 (DOI: 10.1002/pola.27215), Jaeguk Noh, Byung-Jae Chae, Bon-Cheol Ku, and Taek Seung Lee show that conjugated polymer nanoparticles modified with polyarginine exhibit excellent interactions with graphene oxide (GO). This interaction induces the quenching of conjugated polymer nanoparticle fluorescence upon formation of the CPN-GO nanohybrid. Upon exposure to trypsin, the quenched fluorescence is recovered by release of the CPN from the CPN-GO nanohybrid; trypsin cleaves the polyarginine linkage, resulting in weakening of interaction between the CPN and GO.
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