In this study, acrylamide–itaconic acid hydrogels containing different amounts of itaconic acid prepared by irradiating with γ radiation are discussed. They have been used in experiments of swelling, diffusion and bovine serum albumin (BSA) adsorption. Maximum and minimum swellings were observed with water (1520%) and BSA (890%), respectively. Diffusion of water, NaCl and BSA within hydrogels were found to be non-Fickian in character. In the experiments of BSA adsorption, type III adsorption was found. The hydrogel prepared with 60 mg itaconic acid and irradiated at 2.00 kGy was found to be the best adsorption system for BSA. The adsorption capacity of acrylamide–itaconic acid hydrogel was found to exceed that of acrylamide hydrogel by more than 80–100%.

References

1 J. Kost, R. Langer and R. Gombotz, in Hydrogels in Medicine and Pharmacy, Vol. III ( N. A. Peppas, ed.), CRC Press, Florida (1987).
Google Scholar
2 N. F. Cardarelli, Controlled Release Technologies, Vol. 1, CRC Press, Florida (1980).
Google Scholar
3 G. G. Allen, J. W. Beer, M. J. Cauis and R. A. Mikels, Controlled Release Technologies, Vol. 2, CRC Press, Florida (1980).
Google Scholar
4 O. Norio, A. Sakai and N. Sakato, Chem. Abst. 214126q, 103, 801 (1985).
Google Scholar
5 O. Güven and M. Şen, Polymer, 32, 13, 2491 (1990).
Google Scholar
6 W. Gombotz and A. S. Hoffman, in Hydrogels in Medicine and Pharmacy, Vol. 1, ( N. A. Peppas, ed.), CRC Press, Florida (1986).
Google Scholar
7 T. A. Horbett, in Hydrogels in Medicine and Pharmacy, Vol. 1 ( N. A. Peppas, ed.), CRC Press, Florida (1986).
Google Scholar
8 S. Kaetsu, Rad. Phys. Chem., 18, 1, 342 (1981).
Google Scholar
9 A. S. Hoffman, Rad. Phys. Chem., 18, 1, 323 (1981).
Google Scholar
10 A. S. Hoffman, Rad. Phys. Chem., 9, 207 (1977).
10.1016/0146-5724(77)90080-2
CAS Web of Science® Google Scholar
11 F. M. Herman, Encyclopedia of Polymer Science, Vol. 15, John Wiley & Sons, New York (1964).
Google Scholar
12 E. Karadaǧ, D. Saraydin and O. Güven, in Turkish IXth National Symposium on Chemistry and Chemical Engineering ( A. Ikizler, ed.), Trabzon, Turkey (1993).
Google Scholar
13 E. Karadaǧ, Ph.D. Thesis, Sivas, Turkey (1992).
Google Scholar
14 K. R. Scopes, Protein Purification Principles and Practise, Springer-Verlag, New York (1984).
Google Scholar
15 N. A. Peppas and N. M. Franson, J. Polym. Sci., Polym. Phys. Ed., 21, 983 (1983).
10.1002/pol.1983.180210614
CAS Web of Science® Google Scholar
16 J. D. Buckley. and M. Berger, J. Polym. Sci., 56, 175 (1962).
10.1002/pol.1962.1205616315
CAS Web of Science® Google Scholar
17 Z. Y. Ding, J. J. Akinois and R. Salovey, J. Polym. Sci., Part B, Polym. Phys., 29, 1035 (1991).
10.1002/polb.1991.090290815
CAS Web of Science® Google Scholar
18 J. Brandrup and E. H. Immergut, Polymer Handbook, John Wiley, New York (1989).
CAS Web of Science® Google Scholar
19 J. Rosiak, K. Burczak, T. Czolozynska and W. Pekala, Radiat. Phys. Chem., 22, 3, 917 (1983).
10.1016/0146-5724(83)90186-3
Web of Science® Google Scholar
20 J. W. Weber, jr., Physicochemical Process for Water Quality Control, John Wiley, New York (1972).
Google Scholar
21 S. J. Gregg and K. S. W. Sink, Adsorption, Surface Area and Porosity, Academic Press, London (1982).
Google Scholar
22 S. J. Gregg, The Surface Chemistry, Chapman and Hall, London (1965).
Google Scholar
23 N. A. Peppas and G. A. Mikos, in Hydrogels in Medicine and Pharmacy, Vol. 1, ( N. A. Peppas, ed.), CRC Press, Florida (1986).
Google Scholar

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Volume5, Issue10

October 1994

Pages 664-668

Adsorption of bovine serum albumin to acrylamide–itaconic acid hydrogels

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Adsorption of bovine serum albumin to acrylamide–itaconic acid hydrogels

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