Quadriceps muscle endurance in patients with chronic obstructive pulmonary disease
Corresponding Author
Alex Van'T Hul
Department of Physiotherapy, VU University Medical Center, P.O. Box 7057, 1007 MB Amsterdam, The Netherlands
Institute for Fundamental and Clinical Human Movement Science, Vrije Universiteit, Amsterdam, The Netherlands
Department of Physiotherapy, VU University Medical Center, P.O. Box 7057, 1007 MB Amsterdam, The NetherlandsSearch for more papers by this authorJaap Harlaar PhD
Institute for Fundamental and Clinical Human Movement Science, Vrije Universiteit, Amsterdam, The Netherlands
Department of Rehabilitation Medicine, VU University Medical Center, Amsterdam, The Netherlands
Search for more papers by this authorRik Gosselink PhD
Respiratory Rehabilitation and Respiratory Division, University Hospitals, Katholieke Universiteit, Leuven, Belgium
Search for more papers by this authorPeter Hollander PhD
Institute for Fundamental and Clinical Human Movement Science, Vrije Universiteit, Amsterdam, The Netherlands
Faculty of Human Movement Sciences, Vrije Universiteit, Amsterdam, The Netherlands
Search for more papers by this authorPiet Postmus PhD
Department of Pulmonology, VU University Medical Center, Amsterdam, The Netherlands
Search for more papers by this authorGert Kwakkel PhD
Department of Physiotherapy, VU University Medical Center, P.O. Box 7057, 1007 MB Amsterdam, The Netherlands
Institute for Fundamental and Clinical Human Movement Science, Vrije Universiteit, Amsterdam, The Netherlands
Search for more papers by this authorCorresponding Author
Alex Van'T Hul
Department of Physiotherapy, VU University Medical Center, P.O. Box 7057, 1007 MB Amsterdam, The Netherlands
Institute for Fundamental and Clinical Human Movement Science, Vrije Universiteit, Amsterdam, The Netherlands
Department of Physiotherapy, VU University Medical Center, P.O. Box 7057, 1007 MB Amsterdam, The NetherlandsSearch for more papers by this authorJaap Harlaar PhD
Institute for Fundamental and Clinical Human Movement Science, Vrije Universiteit, Amsterdam, The Netherlands
Department of Rehabilitation Medicine, VU University Medical Center, Amsterdam, The Netherlands
Search for more papers by this authorRik Gosselink PhD
Respiratory Rehabilitation and Respiratory Division, University Hospitals, Katholieke Universiteit, Leuven, Belgium
Search for more papers by this authorPeter Hollander PhD
Institute for Fundamental and Clinical Human Movement Science, Vrije Universiteit, Amsterdam, The Netherlands
Faculty of Human Movement Sciences, Vrije Universiteit, Amsterdam, The Netherlands
Search for more papers by this authorPiet Postmus PhD
Department of Pulmonology, VU University Medical Center, Amsterdam, The Netherlands
Search for more papers by this authorGert Kwakkel PhD
Department of Physiotherapy, VU University Medical Center, P.O. Box 7057, 1007 MB Amsterdam, The Netherlands
Institute for Fundamental and Clinical Human Movement Science, Vrije Universiteit, Amsterdam, The Netherlands
Search for more papers by this authorAbstract
The purpose of this study was to compare quadriceps muscle strength (maximal voluntary contraction, MVC), endurance (TLIM), and dynamic work capacity (WLIM) in 89 patients (57 men and 32 women) with chronic obstructive pulmonary disease (COPD) to 31 healthy controls (20 men and 11 women). Compared with the healthy subjects, COPD patients demonstrated statistically significant (P < 0.05) lower values for MVC, TLIM and WLIM. The MVC was 20–30% lower, whereas TLIM and WLIM were 70–80% lower in the patients. Stepwise multiple regression analysis revealed that pulmonary function variables contributed only partially to the explanation of variance in MVC, TLIM, and WLIM. Our results indicate that in patients with COPD, quadriceps muscle endurance and dynamic work capacity are impaired to a greater extent than is quadriceps muscle strength. For rehabilitation purposes, the findings may lead to more specific exercise programs, further enhancing rehabilitation outcomes in terms of functional abilities and social participation. Muscle Nerve 29: 267–274, 2004
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