Volume 29, Issue 3 pp. 447-450
Cases of the Month

Sarcoid polyneuropathy responsive to intravenous immunoglobulin

Dominic Heaney MD

Dominic Heaney MD

Department of Neurology, Royal London Hospital, Whitechapel, London E1 1BB, UK

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Jennian F. Geddes MD

Jennian F. Geddes MD

Department Neuropathology, Royal London Hospital, London, UK

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Kulan Nagendren MB

Kulan Nagendren MB

Department of Clinical Neurophysiology, Royal London Hospital, London, UK

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Michael Swash MD

Corresponding Author

Michael Swash MD

Department of Neurology, Royal London Hospital, Whitechapel, London E1 1BB, UK

Department of Neurology, Royal London Hospital, Whitechapel, London E1 1BB, UKSearch for more papers by this author
First published: 17 February 2004
Citations: 17

Abstract

We describe a 38-year-old woman with a predominantly sensory axonal polyneuropathy in whom a nerve biopsy demonstrated sarcoid granulomas. The neuropathy did not respond to oral steroid therapy but there was a rapid and repeated response to intravenous immunoglobulin, which gradually diminished over subsequent treatments, but remained beneficial. The systemic sarcoidosis remained active. Muscle Nerve 29: 447–450, 2004

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