Comparative Study of Collagen and Gelatin Coatings on Titanium Surfaces
Els Vanderleyden
Polymer Chemistry and Biomaterials Research Group, University of Ghent, Krijgslaan 281 S4, 9000 Ghent, Belgium
Search for more papers by this authorLuc Van Hoorebeke
Department of Physics and Astronomy, University of Ghent, Proeftuinstraat 86, 9000 Ghent, Belgium
Search for more papers by this authorEtienne Schacht
Polymer Chemistry and Biomaterials Research Group, University of Ghent, Krijgslaan 281 S4, 9000 Ghent, Belgium
Search for more papers by this authorCorresponding Author
Peter Dubruel
Polymer Chemistry and Biomaterials Research Group, University of Ghent, Krijgslaan 281 S4, 9000 Ghent, Belgium
Fax: (+32)92644972Search for more papers by this authorEls Vanderleyden
Polymer Chemistry and Biomaterials Research Group, University of Ghent, Krijgslaan 281 S4, 9000 Ghent, Belgium
Search for more papers by this authorLuc Van Hoorebeke
Department of Physics and Astronomy, University of Ghent, Proeftuinstraat 86, 9000 Ghent, Belgium
Search for more papers by this authorEtienne Schacht
Polymer Chemistry and Biomaterials Research Group, University of Ghent, Krijgslaan 281 S4, 9000 Ghent, Belgium
Search for more papers by this authorCorresponding Author
Peter Dubruel
Polymer Chemistry and Biomaterials Research Group, University of Ghent, Krijgslaan 281 S4, 9000 Ghent, Belgium
Fax: (+32)92644972Search for more papers by this authorAbstract
The vast majority of studies in the bone tissue engineering field are focused on the surface modification of titanium scaffolds to obtain integration of the scaffold in the surrounding bone tissue. Our approach consisted in benefiting from the advantages of the cell-interaction capabilities of collagen and gelatin. The biopolymers were immobilised onto the Ti surface through different methods and the stability of the obtained coatings was determined. The obtained results reveal that covalent immobilisation of collagen and gelatin is required to obtain stable surface coatings.
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