Volume 309-310, Issue 1 pp. 190-198
Article

Comparative Study of Collagen and Gelatin Coatings on Titanium Surfaces

Els Vanderleyden

Els Vanderleyden

Polymer Chemistry and Biomaterials Research Group, University of Ghent, Krijgslaan 281 S4, 9000 Ghent, Belgium

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Luc Van Hoorebeke

Luc Van Hoorebeke

Department of Physics and Astronomy, University of Ghent, Proeftuinstraat 86, 9000 Ghent, Belgium

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Etienne Schacht

Etienne Schacht

Polymer Chemistry and Biomaterials Research Group, University of Ghent, Krijgslaan 281 S4, 9000 Ghent, Belgium

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Peter Dubruel

Corresponding Author

Peter Dubruel

Polymer Chemistry and Biomaterials Research Group, University of Ghent, Krijgslaan 281 S4, 9000 Ghent, Belgium

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First published: 15 December 2011
Citations: 5

Abstract

The vast majority of studies in the bone tissue engineering field are focused on the surface modification of titanium scaffolds to obtain integration of the scaffold in the surrounding bone tissue. Our approach consisted in benefiting from the advantages of the cell-interaction capabilities of collagen and gelatin. The biopolymers were immobilised onto the Ti surface through different methods and the stability of the obtained coatings was determined. The obtained results reveal that covalent immobilisation of collagen and gelatin is required to obtain stable surface coatings.

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