Clinical Report

Ultrasound-Guided Laser Ablation Versus Microwave Ablation for Patients With Unifocal Papillary Thyroid Microcarcinoma: A Retrospective Study

Wei Zhou

orcid.org/0000-0002-9610-3113

Department of Ultrasound, Rui Jin Hospital, School of Medicine, Shanghai Jiao Tong University, 197 Ruijin 2 Rd, Shanghai, 200025 China

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Xiaofeng Ni,

Xiaofeng Ni

Department of Ultrasound, Rui Jin Hospital, School of Medicine, Shanghai Jiao Tong University, 197 Ruijin 2 Rd, Shanghai, 200025 China

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Shangyan Xu,

Shangyan Xu

Department of Ultrasound, Rui Jin Hospital, School of Medicine, Shanghai Jiao Tong University, 197 Ruijin 2 Rd, Shanghai, 200025 China

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Lu Zhang,

Lu Zhang

Department of Ultrasound, Rui Jin Hospital, School of Medicine, Shanghai Jiao Tong University, 197 Ruijin 2 Rd, Shanghai, 200025 China

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Yudong Chen,

Yudong Chen

Department of Ultrasound, Rui Jin Hospital, School of Medicine, Shanghai Jiao Tong University, 197 Ruijin 2 Rd, Shanghai, 200025 China

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Weiwei Zhan,

Corresponding Author

Weiwei Zhan

[email protected]

Department of Ultrasound, Rui Jin Hospital, School of Medicine, Shanghai Jiao Tong University, 197 Ruijin 2 Rd, Shanghai, 200025 China

Correspondence to: Weiwei Zhan, MD, Department of Ultrasound, Rui Jin Hospital, School of Medicine, Shanghai Jiao Tong University, 197 Ruijin 2 Rd, 200025 Shanghai, China. E-mail: [email protected]

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Wei Zhou,

Wei Zhou

orcid.org/0000-0002-9610-3113

Department of Ultrasound, Rui Jin Hospital, School of Medicine, Shanghai Jiao Tong University, 197 Ruijin 2 Rd, Shanghai, 200025 China

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Xiaofeng Ni,

Xiaofeng Ni

Department of Ultrasound, Rui Jin Hospital, School of Medicine, Shanghai Jiao Tong University, 197 Ruijin 2 Rd, Shanghai, 200025 China

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Shangyan Xu,

Shangyan Xu

Department of Ultrasound, Rui Jin Hospital, School of Medicine, Shanghai Jiao Tong University, 197 Ruijin 2 Rd, Shanghai, 200025 China

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Lu Zhang,

Lu Zhang

Department of Ultrasound, Rui Jin Hospital, School of Medicine, Shanghai Jiao Tong University, 197 Ruijin 2 Rd, Shanghai, 200025 China

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Yudong Chen,

Yudong Chen

Department of Ultrasound, Rui Jin Hospital, School of Medicine, Shanghai Jiao Tong University, 197 Ruijin 2 Rd, Shanghai, 200025 China

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Weiwei Zhan,

Corresponding Author

Weiwei Zhan

[email protected]

Department of Ultrasound, Rui Jin Hospital, School of Medicine, Shanghai Jiao Tong University, 197 Ruijin 2 Rd, Shanghai, 200025 China

Correspondence to: Weiwei Zhan, MD, Department of Ultrasound, Rui Jin Hospital, School of Medicine, Shanghai Jiao Tong University, 197 Ruijin 2 Rd, 200025 Shanghai, China. E-mail: [email protected]

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First published: 26 March 2020

https://doi.org/10.1002/lsm.23238

Citations: 12

Conflict of Interest Disclosures: All authors have completed and submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest and none were reported.

Contract grant sponsor: Fund project of Shanghai Huangpu district health and family planning commission; Contract grant number: HKM201801.

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Abstract

Background and Objectives

The objective of this study is to compare the efficacy and the safety of ultrasound-guided microwave ablation (MWA) and laser ablation (LA) for the treatment of papillary thyroid microcarcinoma (PTMC).

Study Design/Materials and Methods

A total of 67 patients with unifocal PTMC were studied retrospectively, including 33 cases who underwent MWA (MWA group) and 34 cases who received LA (LA group). The follow-up consisted of thyroid function tests, ultrasonography, contrast-enhanced ultrasonography (CEUS), and chest X-ray or computed tomography scan. The treatment response and complications were compared between the two groups.

Results

The follow-up time for the MWA and LA group was 23.3 ± 4.4 and 22.8 ± 4.1 months, respectively. All the ablations were successfully performed as planned without complementary ablations, and it was confirmed by CEUS after treatment in both groups. It was observed that, at the last follow-up, the mean largest diameter decreased from 5.0 ± 1.4 mm to 0.1 ± 0.4 mm (MWA group) and from 4.5 ± 1.6 mm to 0.6 ± 1.2 mm(LA group) (P < 0.05 for both). The average volume reduced from 51.9 ± 40.8 to 0.2 ± 1.0 mm³ (MWA group) and from 38.5 ± 43.0 to 1.3 ± 3.8 mm³ (LA group) (P < 0.05 for both). The complication rates did not differ between the MWA group (9.1%) and the LA group (2.9%) (P > 0.05). No local recurrence or distant metastasis occurred in either group.

Conclusions

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Volume52, Issue9

November 2020

Pages 855-862

Ultrasound-Guided Laser Ablation Versus Microwave Ablation for Patients With Unifocal Papillary Thyroid Microcarcinoma: A Retrospective Study

Abstract

Background and Objectives

Study Design/Materials and Methods

Results

Conclusions

REFERENCES

Citing Literature

References

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Ultrasound-Guided Laser Ablation Versus Microwave Ablation for Patients With Unifocal Papillary Thyroid Microcarcinoma: A Retrospective Study

Abstract

Background and Objectives

Study Design/Materials and Methods

Results

Conclusions

REFERENCES

Citing Literature

References

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