Volume 134, Issue 2 pp. 645-647
Case Report

CSF-Venous Fistula of the Clival Skull Base: A Unique Case Study and Literature Review

Jordan K. Simmons MD

Jordan K. Simmons MD

Division of Otolaryngology, Cedars-Sinai Medical Center, Los Angeles, California, U.S.A.

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Wasiq Nadeem BS

Wasiq Nadeem BS

Division of Otolaryngology, Cedars-Sinai Medical Center, Los Angeles, California, U.S.A.

San Antonio School of Medicine, University of Texas, San Antonio, Texas, U.S.A.

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Marcel M. Maya MD

Marcel M. Maya MD

Department of Imaging, Cedars-Sinai Medical Center, Los Angeles, California, U.S.A.

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Arthur W. Wu MD

Arthur W. Wu MD

Division of Otolaryngology, Cedars-Sinai Medical Center, Los Angeles, California, U.S.A.

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Wouter I. Schievink MD

Wouter I. Schievink MD

Department of Neurosurgery, Cedars-Sinai Medical Center, Los Angeles, California, U.S.A.

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Adam N. Mamelak MD

Adam N. Mamelak MD

Department of Neurosurgery, Cedars-Sinai Medical Center, Los Angeles, California, U.S.A.

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Dennis M. Tang MD

Corresponding Author

Dennis M. Tang MD

Division of Otolaryngology, Cedars-Sinai Medical Center, Los Angeles, California, U.S.A.

Send correspondence to Dennis M. Tang, Division of Otolaryngology, Cedars-Sinai Medical Center, 8631 W 3rd St, Suite 915E, Los Angeles, CA 90048. Email: [email protected]

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First published: 08 September 2023
Editor's Note: This Manuscript was accepted for publication on August 22, 2023.

The authors have no funding, financial relationships, or conflicts of interest to disclose.

Abstract

An adolescent male presented with orthostatic headaches following head trauma. MRI showed cerebellar tonsil displacement and a bony defect in the clival skull base. Digital subtraction myelography (DSM) confirmed a cerebrospinal fluid-venous fistula (CVF). This was repaired endoscopically. CVFs cause uncontrolled flow of CSF into the venous system resulting in symptoms of intracranial hypotension. They're often difficult to identify on initial imaging. This is the first reported CVF originating in the central skull base, and the first treated via endoscopic trans-nasal approach. CVFs may elude initial imaging, making DSM crucial for unexplained spontaneous intracranial hypotension. Laryngoscope, 134:645–647, 2024

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