Review Article
From Morphology to Therapeutic Strategies: Exploring New Applications of Ultrasound for Diabetic Peripheral Neuropathy Diagnosis and Management
Yanfeng Jiang MM,
Xiatian Liu PhD,
Zhenzhen Jiang PhD,
Yanfeng Jiang MM
Department of Ultrasound, The First Affiliated Hospital of Shaoxing University, Shaoxing, China
Department of Ultrasound, Shaoxing People's Hospital, Shaoxing, China
Search for more papers by this authorCorresponding Author
Xiatian Liu PhD
Department of Ultrasound, The First Affiliated Hospital of Shaoxing University, Shaoxing, China
Department of Ultrasound, Shaoxing People's Hospital, Shaoxing, China
Address correspondence to Zhenzhen Jiang, PhD, Department of Ultrasound, The First Affiliated Hospital of Shaoxing University, Shaoxing, 312000, China.
E-mail: [email protected]
Xiatian Liu, PhD, Department of Ultrasound, The First Affiliated Hospital of Shaoxing University, Shaoxing, 312000, China.
E-mail: [email protected]
Search for more papers by this authorCorresponding Author
Zhenzhen Jiang PhD
Department of Ultrasound, The First Affiliated Hospital of Shaoxing University, Shaoxing, China
Department of Ultrasound, Shaoxing People's Hospital, Shaoxing, China
Address correspondence to Zhenzhen Jiang, PhD, Department of Ultrasound, The First Affiliated Hospital of Shaoxing University, Shaoxing, 312000, China.
E-mail: [email protected]
Xiatian Liu, PhD, Department of Ultrasound, The First Affiliated Hospital of Shaoxing University, Shaoxing, 312000, China.
E-mail: [email protected]
Search for more papers by this authorYanfeng Jiang MM,
Xiatian Liu PhD,
Zhenzhen Jiang PhD,
Yanfeng Jiang MM
Department of Ultrasound, The First Affiliated Hospital of Shaoxing University, Shaoxing, China
Department of Ultrasound, Shaoxing People's Hospital, Shaoxing, China
Search for more papers by this authorCorresponding Author
Xiatian Liu PhD
Department of Ultrasound, The First Affiliated Hospital of Shaoxing University, Shaoxing, China
Department of Ultrasound, Shaoxing People's Hospital, Shaoxing, China
Address correspondence to Zhenzhen Jiang, PhD, Department of Ultrasound, The First Affiliated Hospital of Shaoxing University, Shaoxing, 312000, China.
E-mail: [email protected]
Xiatian Liu, PhD, Department of Ultrasound, The First Affiliated Hospital of Shaoxing University, Shaoxing, 312000, China.
E-mail: [email protected]
Search for more papers by this authorCorresponding Author
Zhenzhen Jiang PhD
Department of Ultrasound, The First Affiliated Hospital of Shaoxing University, Shaoxing, China
Department of Ultrasound, Shaoxing People's Hospital, Shaoxing, China
Address correspondence to Zhenzhen Jiang, PhD, Department of Ultrasound, The First Affiliated Hospital of Shaoxing University, Shaoxing, 312000, China.
E-mail: [email protected]
Xiatian Liu, PhD, Department of Ultrasound, The First Affiliated Hospital of Shaoxing University, Shaoxing, 312000, China.
E-mail: [email protected]
Search for more papers by this authorThis work was supported by Medical and Health Science and Technology Program of Zhejiang Province (2024KY468), Shaoxing Medical Key Discipline (2019SZD05), and Graduate Research Program of Shaoxing University, Zhejiang Province (Y20230311).
The authors declare no competing interests.
The authors thank all the staff and participants of this study for their important contributions.
Abstract
Diabetic peripheral neuropathy (DPN) is a common complication of diabetes that can result in severe lower limb pain and amputation. Early detection and treatment of DPN are vital, but this condition is often missed due to a lack of symptoms and the insensitivity of testing methods. This article reviews various ultrasound imaging modalities in the direct and indirect evaluation of peripheral neuropathy. Moreover, how ultrasound-related therapeutic strategies are playing a role in clinical treatment is discussed. Finally, the application of innovative methodologies in the diagnosis of DPN, including ultrasound attenuation, photoacoustic imaging, and artificial intelligence, is described.
Open Research
Data Availability Statement
Data sharing not applicable to this article as no datasets were generated or analysed during the current study.
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