Ewing's sarcoma of bone: Oncologic and functional results
Auke J. S. Renard MD
Departments of Orthopaedics, University of Nijmegen, Nijmegen, The Netherlands
Search for more papers by this authorCorresponding Author
Dr. René P. H. Veth MD, PhD
Departments of Orthopaedics, University of Nijmegen, Nijmegen, The Netherlands
Department of Orthopaedics, University Hospital of St. Radboud, University of Nijmegen, P.O. Box 9101, NL-6500 HB, Nijmegen, The NetherlandsSearch for more papers by this authorMaciej Pruszczynksi MD, PhD
Departments of Pathology, University of Nijmegen, Nijmegen, The Netherlands
Search for more papers by this authorJaap Hoogenhout MD, PhD
Departments of Radiotherapy, University of Nijmegen, Nijmegen, The Netherlands
Search for more papers by this authorJos Bökkerink MD, PhD
Departments of Pediatric Oncology, University of Nijmegen, Nijmegen, The Netherlands
Search for more papers by this authorFrans J. M. Van Der Staak
Departments of Pediatric Surgery, University of Nijmegen, Nijmegen, The Netherlands
Search for more papers by this authorTheo Wobbes MD, PhD
Departments of General Surgery, University of Nijmegen, Nijmegen, The Netherlands
Search for more papers by this authorJosef A. M. Lemmens MD, PhD
Departments of Radiology, University of Nijmegen, Nijmegen, The Netherlands
Search for more papers by this authorRené van Hoesel MD, PhD
Departments of Medical Oncology, University Hospital of St. Radboud, University of Nijmegen, Nijmegen, The Netherlands
Search for more papers by this authorJim R. Van Horn MD, PhD
Department of Orthopaedics, University Hospital of Croningen, Groningen, The Netherlands
Search for more papers by this authorAuke J. S. Renard MD
Departments of Orthopaedics, University of Nijmegen, Nijmegen, The Netherlands
Search for more papers by this authorCorresponding Author
Dr. René P. H. Veth MD, PhD
Departments of Orthopaedics, University of Nijmegen, Nijmegen, The Netherlands
Department of Orthopaedics, University Hospital of St. Radboud, University of Nijmegen, P.O. Box 9101, NL-6500 HB, Nijmegen, The NetherlandsSearch for more papers by this authorMaciej Pruszczynksi MD, PhD
Departments of Pathology, University of Nijmegen, Nijmegen, The Netherlands
Search for more papers by this authorJaap Hoogenhout MD, PhD
Departments of Radiotherapy, University of Nijmegen, Nijmegen, The Netherlands
Search for more papers by this authorJos Bökkerink MD, PhD
Departments of Pediatric Oncology, University of Nijmegen, Nijmegen, The Netherlands
Search for more papers by this authorFrans J. M. Van Der Staak
Departments of Pediatric Surgery, University of Nijmegen, Nijmegen, The Netherlands
Search for more papers by this authorTheo Wobbes MD, PhD
Departments of General Surgery, University of Nijmegen, Nijmegen, The Netherlands
Search for more papers by this authorJosef A. M. Lemmens MD, PhD
Departments of Radiology, University of Nijmegen, Nijmegen, The Netherlands
Search for more papers by this authorRené van Hoesel MD, PhD
Departments of Medical Oncology, University Hospital of St. Radboud, University of Nijmegen, Nijmegen, The Netherlands
Search for more papers by this authorJim R. Van Horn MD, PhD
Department of Orthopaedics, University Hospital of Croningen, Groningen, The Netherlands
Search for more papers by this authorAbstract
This paper describes 29 patients with Ewing's sarcoma of bone treated between 1975 and 1990 at the University of Nijmegen Hospital, Nijmegen, The Netherlands. Osteomyelitis was the primary diagnosis in 24%.
Treatment consisted of chemotherapy in combination with surgery and/or radiotherapy. Nine patients received radiotherapy only; five of them died of disease. Five patients underwent an intralesional excision; four of them died of disease. Twelve patients underwent a wide excision; there is no evidence of disease in any of them. Three patients underwent a radical disarticulation; all died of disease. The disease-free survival at 1.5 years was 66%. This figure at 5 years was 55%. After wide excision and reconstruction in tumors of expendable, femoral or radial bones good functional results were obtained in all cases. © 1995 Wiley-Liss, Inc.
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