Review Article
Revisiting the gastric pull-up for pharyngoesophageal reconstruction: A systematic review and meta-analysis of mortality and morbidity
Oleksandr Butskiy BSc, MD,
Ronak Rahmanian BSc, MD,
Richard A. White BSc, MSc,
Scott Durham MD, FRCSC,
Donald W. Anderson MD, FRCSC,
Eitan Prisman MD, FRCSC,
Corresponding Author
Oleksandr Butskiy BSc, MD
Division of Otolaryngology—Head and Neck Surgery, Vancouver General Hospital, Vancouver, British Columbia, Canada
University of British Columbia, Vancouver, British Columbia, Canada
Correspondence to: Oleksandr Butskiy, BSc, MD, Gordon and Leslie Diamond Health Care Centre, 4th Floor 4299B, 2775 Laurel Street, Vancouver, BC V5Z 1M9, Canada. Fax: +1-778-373-1063; E-mail: [email protected]
Search for more papers by this authorRonak Rahmanian BSc, MD
Division of Otolaryngology—Head and Neck Surgery, Vancouver General Hospital, Vancouver, British Columbia, Canada
University of British Columbia, Vancouver, British Columbia, Canada
Search for more papers by this authorRichard A. White BSc, MSc
Statistical Consulting and Research Laboratory, Department of Statistics, University of British Columbia, Vancouver, British Columbia, Canada
Search for more papers by this authorScott Durham MD, FRCSC
Division of Otolaryngology—Head and Neck Surgery, Vancouver General Hospital, Vancouver, British Columbia, Canada
University of British Columbia, Vancouver, British Columbia, Canada
Search for more papers by this authorDonald W. Anderson MD, FRCSC
Division of Otolaryngology—Head and Neck Surgery, Vancouver General Hospital, Vancouver, British Columbia, Canada
University of British Columbia, Vancouver, British Columbia, Canada
Search for more papers by this authorEitan Prisman MD, FRCSC
Division of Otolaryngology—Head and Neck Surgery, Vancouver General Hospital, Vancouver, British Columbia, Canada
University of British Columbia, Vancouver, British Columbia, Canada
Search for more papers by this authorOleksandr Butskiy BSc, MD,
Ronak Rahmanian BSc, MD,
Richard A. White BSc, MSc,
Scott Durham MD, FRCSC,
Donald W. Anderson MD, FRCSC,
Eitan Prisman MD, FRCSC,
Corresponding Author
Oleksandr Butskiy BSc, MD
Division of Otolaryngology—Head and Neck Surgery, Vancouver General Hospital, Vancouver, British Columbia, Canada
University of British Columbia, Vancouver, British Columbia, Canada
Correspondence to: Oleksandr Butskiy, BSc, MD, Gordon and Leslie Diamond Health Care Centre, 4th Floor 4299B, 2775 Laurel Street, Vancouver, BC V5Z 1M9, Canada. Fax: +1-778-373-1063; E-mail: [email protected]
Search for more papers by this authorRonak Rahmanian BSc, MD
Division of Otolaryngology—Head and Neck Surgery, Vancouver General Hospital, Vancouver, British Columbia, Canada
University of British Columbia, Vancouver, British Columbia, Canada
Search for more papers by this authorRichard A. White BSc, MSc
Statistical Consulting and Research Laboratory, Department of Statistics, University of British Columbia, Vancouver, British Columbia, Canada
Search for more papers by this authorScott Durham MD, FRCSC
Division of Otolaryngology—Head and Neck Surgery, Vancouver General Hospital, Vancouver, British Columbia, Canada
University of British Columbia, Vancouver, British Columbia, Canada
Search for more papers by this authorDonald W. Anderson MD, FRCSC
Division of Otolaryngology—Head and Neck Surgery, Vancouver General Hospital, Vancouver, British Columbia, Canada
University of British Columbia, Vancouver, British Columbia, Canada
Search for more papers by this authorEitan Prisman MD, FRCSC
Division of Otolaryngology—Head and Neck Surgery, Vancouver General Hospital, Vancouver, British Columbia, Canada
University of British Columbia, Vancouver, British Columbia, Canada
Search for more papers by this authorAbstract
Gastric pull-up (GPU) is among the oldest techniques for reconstructing the pharyngoesophageal junction following cancer resection. This review examines morbidity and mortality rates following GPU pharyngoesophageal junction reconstruction from 1959 until present: 77 studies, 2,705 patients. The odds of mortality, anastomotic complications, and other complications decreased by 37.2% (95%CI = 28.0–45.3%; P < 0.0001), 8.0% (95%CI = −2.1 to 17.1%; P = 0.12), 21.0% (95%CI 3.5–35.2%; P = 0.021) per decade respectively. J. Surg. Oncol. 2016;114:907–914. © 2016 Wiley Periodicals, Inc.
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