Volume 43, Issue 1 pp. 46-48
Article

Microtoxicology. X. Colorimetric reactions and optical crystallographic properties of five synthetic antispasmodics

Thomas J. Haley

Thomas J. Haley

School of Medicine, University of California at Los Angeles

Chief o the Division of Pharmacology and Toxicology, Atomic Energy Project and Associate Clinical Professor of Industrial Medicine, School of Medicine, University of California at Los Angeles.

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George L. Keenan

George L. Keenan

School of Medicine, University of California at Los Angeles

Formerly Microanalyst. Food and Drug Administration. Deceased.

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First published: January 1954

Abstract

The antispasmodics Profenil Citrate, Syntropan phosphate, Trasentin hydrochloride, Pavatrine hydrochloride, and Lacbesine chloride were subjected to a large number of colorimetric and precipitation reagents. Although definite differences between these drugs were observed, the drugs were difficult to identify b these methods. On the other hand, their optical crystallographic properties eagle a positive identification to be made from very small amounts of material. Combination of these methods with melting point determinations may be useful to the toxicological chemist.

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