MRI of Temporomandibular Joint Disorders: Recent Advances and Future Directions
Xin Xiong PhD
State Key Laboratory of Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, China
These authors contributed equally to this work.
Search for more papers by this authorZheng Ye PhD
Department of Radiology, West China Hospital, Sichuan University, Chengdu, China
These authors contributed equally to this work.
Search for more papers by this authorHehan Tang PhD
Department of Radiology, West China Hospital, Sichuan University, Chengdu, China
Search for more papers by this authorYi Wei PhD
Department of Radiology, West China Hospital, Sichuan University, Chengdu, China
Search for more papers by this authorCorresponding Author
Yang Liu PhD
State Key Laboratory of Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, China
Address reprint requests to: Y.L., State Key Laboratory of Oral Diseases, West China Hospital of Stomatology, Sichuan University, No.14, Section 3, South Renmin Road, Chengdu 610041, China. E-mail: [email protected], or B.S., Department of Radiology, West China Hospital, Sichuan University, No. 37 Guoxue Alley, Chengdu 610041, China. E-mail: [email protected]
Search for more papers by this authorCorresponding Author
Bin Song MD
Department of Radiology, West China Hospital, Sichuan University, Chengdu, China
Address reprint requests to: Y.L., State Key Laboratory of Oral Diseases, West China Hospital of Stomatology, Sichuan University, No.14, Section 3, South Renmin Road, Chengdu 610041, China. E-mail: [email protected], or B.S., Department of Radiology, West China Hospital, Sichuan University, No. 37 Guoxue Alley, Chengdu 610041, China. E-mail: [email protected]
Search for more papers by this authorXin Xiong PhD
State Key Laboratory of Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, China
These authors contributed equally to this work.
Search for more papers by this authorZheng Ye PhD
Department of Radiology, West China Hospital, Sichuan University, Chengdu, China
These authors contributed equally to this work.
Search for more papers by this authorHehan Tang PhD
Department of Radiology, West China Hospital, Sichuan University, Chengdu, China
Search for more papers by this authorYi Wei PhD
Department of Radiology, West China Hospital, Sichuan University, Chengdu, China
Search for more papers by this authorCorresponding Author
Yang Liu PhD
State Key Laboratory of Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, China
Address reprint requests to: Y.L., State Key Laboratory of Oral Diseases, West China Hospital of Stomatology, Sichuan University, No.14, Section 3, South Renmin Road, Chengdu 610041, China. E-mail: [email protected], or B.S., Department of Radiology, West China Hospital, Sichuan University, No. 37 Guoxue Alley, Chengdu 610041, China. E-mail: [email protected]
Search for more papers by this authorCorresponding Author
Bin Song MD
Department of Radiology, West China Hospital, Sichuan University, Chengdu, China
Address reprint requests to: Y.L., State Key Laboratory of Oral Diseases, West China Hospital of Stomatology, Sichuan University, No.14, Section 3, South Renmin Road, Chengdu 610041, China. E-mail: [email protected], or B.S., Department of Radiology, West China Hospital, Sichuan University, No. 37 Guoxue Alley, Chengdu 610041, China. E-mail: [email protected]
Search for more papers by this authorAbstract
Temporomandibular joint disorders (TMDs) are a prevalent disease covering pain and dysfunction of temporomandibular joints and masticatory muscles, which can be detrimental to quality of life. Magnetic resonance imaging (MRI) is a powerful and noninvasive tool for the imaging and understanding of TMD. With the recent technical development of dynamic and quantitative MRI techniques, including diffusion-weighted imaging, T2 mapping, and ultrashort/zero echo time, it is now feasible in TMD imaging and has been preliminarily investigated with promising results. In this review we will discuss the recent advances of MRI techniques in TMD and its future directions, and hope to highlight the scientific potential and clinical value of novel MRI techniques in diagnosing and treating TMD.
Level of Evidence
4
Technical Efficacy Stage
3
Supporting Information
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References
- 1Scrivani SJ, Keith DA, Kaban LB. Temporomandibular disorders. N Engl J Med 2008; 359: 2693-2705.
- 2Ahmad M, Hollender L, Anderson Q, et al. Research diagnostic criteria for temporomandibular disorders (RDC/TMD): Development of image analysis criteria and examiner reliability for image analysis. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2009; 107: 844-860.
- 3National Institute of Dental and Craniofacial Research, Data & statistics of facial pain. https://www.nidcr.nih.gov/research/data-statistics/facial-pain. Accessed April 1, 2020.
- 4Dahlström L, Carlsson GE. Temporomandibular disorders and oral health-related quality of life. A systematic review. Acta Odontol Scand 2010; 68: 80-85.
- 5Almeida FT, Pacheco-Pereira C, Flores-Mir C, Le LH, Jaremko JL, Major PW. Diagnostic ultrasound assessment of temporomandibular joints: A systematic review and meta-analysis. Dentomaxillofac Radiol 2019; 48:20180144.
- 6Larheim T, Abrahamsson A, Kristensen M, Arvidsson L. Temporomandibular joint diagnostics using CBCT. Dentomaxillofac Radiol 2015; 44:20140235.
- 7Matsubara R, Yanagi Y, Oki K, et al. Assessment of MRI findings and clinical symptoms in patients with temporomandibular joint disorders. Dentomaxillofac Radiol 2018; 47:20170412.
- 8Yilmaz D, Kamburoglu K. Comparison of the effectiveness of high resolution ultrasound with MRI in patients with temporomandibular joint disorders. Dentomaxillofac Radiol 2019; 48:20180349.
- 9Tomas X, Pomes J, Berenguer J, et al. MR imaging of temporomandibular joint dysfunction: A pictorial review. Radiographics 2006; 26: 765-781.
- 10Ma RH, Li G, Sun Y, Meng JH, Zhao YP, Zhang H. Application of fused image in detecting abnormalities of temporomandibular joint. Dentomaxillofac Radiol 2019; 48:20180129.
- 11Alkhader M, Ohbayashi N, Tetsumura A, et al. Diagnostic performance of magnetic resonance imaging for detecting osseous abnormalities of the temporomandibular joint and its correlation with cone beam computed tomography. Dentomaxillofac Radiol 2010; 39: 270-276.
- 12Eberhard L, Giannakopoulos NN, Rohde S, Schmitter M. Temporomandibular joint (TMJ) disc position in patients with TMJ pain assessed by coronal MRI. Dentomaxillofac Radiol 2013; 42:20120199.
- 13Karlo CA, Patcas R, Kau T, et al. MRI of the temporo-mandibular joint: Which sequence is best suited to assess the cortical bone of the mandibular condyle? A cadaveric study using micro-CT as the standard of reference. Eur Radiol 2012; 22: 1579-1585.
- 14Yoshida M, Honda E, Ozawa E, et al. Principles of the magnetic resonance imaging movie method for articulatory movement. Oral Radiol 2018; 35: 91-100.
- 15Nikkuni Y, Nishiyama H, Hayashi T. Clinical significance of T2 mapping MRI for the evaluation of masseter muscle pain in patients with temporomandibular joint disorders. Oral Radiol 2013; 29: 50-55.
- 16Bae WC, Biswas R, Statum S, Sah RL, Chung CB. Sensitivity of quantitative UTE MRI to the biomechanical property of the temporomandibular joint disc. Skeletal Radiol 2014; 43: 1217-1223.
- 17Shiraishi T, Chikui T, Inadomi D, Kagawa T, Yoshiura K, Yuasa K. Evaluation of diffusion parameters and T2 values of the masseter muscle during jaw opening, clenching, and rest. Acta Radiol 2012; 53: 81-86.
- 18Lee C, Jeon KJ, Han S-S, et al. CT-like MRI using the zero-TE technique for osseous changes of the TMJ. Dentomaxillofac Radiol 2020; 49:20190272.
- 19Scapino RP, Obrez A, Greising D. Organization and function of the collagen fiber system in the human temporomandibular joint disk and its attachments. Cells Tissues Organs 2006; 182: 201-225.
- 20Ingawale S, Goswami T. Temporomandibular joint: Disorders, treatments, and biomechanics. Ann Biomed Eng 2009; 37: 976-996.
- 21Lam DK, Sessle BJ, Cairns BE, Hu JW. Neural mechanisms of temporomandibular joint and masticatory muscle pain: A possible role for peripheral glutamate receptor mechanisms. Pain Res Manag 2005; 10: 145-152.
- 22Liu X, Zhang S, Yang C, et al. Correlation between disc displacements and locations of disc perforation in the temporomandibular joint. Dentomaxillofac Radiol 2010; 39: 149-156.
- 23Cevidanes L, Hajati A-K, Paniagua B, et al. Quantification of condylar resorption in temporomandibular joint osteoarthritis. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2010; 110: 110-117.
- 24Manoliu A, Spinner G, Wyss M, et al. Quantitative and qualitative comparison of MR imaging of the temporomandibular joint at 1.5 and 3.0 T using an optimized high-resolution protocol. Dentomaxillofac Radiol 2016; 45:20150240.
- 25Manoliu A, Spinner G, Wyss M, et al. Comparison of a 32-channel head coil and a 2-channel surface coil for MR imaging of the temporomandibular joint at 3.0 T. Dentomaxillofac Radiol 2016; 45:20150420.
- 26Tomura N, Otani T, Narita K, et al. Visualization of anterior disc displacement in temporomandibular disorders on contrast-enhanced magnetic resonance imaging: Comparison with T2-weighted, proton density-weighted, and precontrast T1-weighted imaging. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2007; 103: 260-266.
- 27Otonari-Yamamoto M, Imoto K. Differences in signal intensities of temporomandibular joint (TMJ) effusion on fluid-attenuated inversion recovery (FLAIR) images. Oral Radiol 2018; 34: 245-250.
- 28Imoto K, Otonari-Yamamoto M, Nishikawa K, Sano T, Yamamoto A. Potential of fluid-attenuated inversion recovery (FLAIR) in identification of temporomandibular joint effusion compared with T2-weighted images. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2011; 112: 243-248.
- 29Yura S, Nobata K, Shima T. Diagnostic accuracy on fat-saturated T2 weighted MRI for diagnosis of intra-articular adhesions of the temporomandibular joint. Dentomaxillofac Radiol 2012; 41: 230-233.
- 30Iwasaki H, Kubo H, Harada M, Nishitani H. Temporomandibular joint and 3.0 T pseudodynamic magnetic resonance imaging. Part 1: Evaluation of condylar and disc dysfunction. Dentomaxillofac Radiol 2010; 39: 475-485.
- 31Iwasaki H, Kubo H, Harada M, Nishitani H, Ohashi Y. Temporomandibular joint and 3.0 T pseudodynamic magnetic resonance imaging. Part 2: Evaluation of articular disc obscurity. Dentomaxillofac Radiol 2010; 39: 486-493.
- 32Lin WC, Lo CP, Chiang IC, et al. The use of pseudo-dynamic magnetic resonance imaging for evaluating the relationship between temporomandibular joint anterior disc displacement and joint pain. Int J Oral Maxillofac Surg 2012; 41: 1501-1504.
- 33Uecker M, Zhang S, Voit D, Merboldt KD, Frahm J. Real-time MRI: Recent advances using radial FLASH. Imaging Med 2012; 4: 461-476.
- 34Seemann R, Czerny C, Schicho K, et al. Pseudodynamic MRI differs from natural opening of the temporomandibular joint. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2008; 105: 371-378.
- 35Zhang S, Block KT, Frahm J. Magnetic resonance imaging in real time: Advances using radial FLASH. J Magn Reson Imaging 2010; 31: 101-109.
- 36Yen P, Katzberg RW, Buonocore MH, Sonico J. Dynamic MR imaging of the temporomandibular joint using a balanced steady-state free precession sequence at 3T. AJNR Am J Neuroradiol 2013; 34: E24-E26.
- 37Azuma T, Ito J, Kutsuki M, Nakai R, Fujita S, Tsutsumi S. Analysis of the mandibular movement by simultaneous multisection continuous ultrafast MRI. Magn Reson Imaging 2009; 27: 423-433.
- 38Sun Q, M-j D, X-f T, Yu Q, Li K-c, Yang C. Dynamic MR imaging of temporomandibular joint: An initial assessment with fast imaging employing steady-state acquisition sequence. Magn Reson Imaging 2015; 33: 270-275.
- 39Uecker M, Zhang S, Voit D, Karaus A, Merboldt KD, Frahm J. Real-time MRI at a resolution of 20 ms. NMR Biomed 2010; 23: 986-994.
- 40Wundrak S, Paul J, Ulrici J, Hell E, Rasche V. A small surrogate for the golden angle in time-resolved radial MRI based on generalized Fibonacci sequences. IEEE Trans Med Imaging 2015; 34: 1262-1269.
- 41Wundrak S, Paul J, Ulrici J, et al. Golden ratio sparse MRI using tiny golden angles. Magn Reson Med 2016; 75: 2372-2378.
- 42Krohn S, Gersdorff N, Wassmann T, et al. Real-time MRI of the temporomandibular joint at 15 frames per second-a feasibility study. Eur J Radiol 2016; 85: 2225-2230.
- 43Frahm J, Voit D, Uecker M. Real-time magnetic resonance imaging: Radial gradient-Echo sequences with nonlinear inverse reconstruction. Invest Radiol 2019; 54: 757-766.
- 44Krohn S, Joseph AA, Voit D, et al. Multi-slice real-time MRI of temporomandibular joint dynamics. Dentomaxillofac Radiol 2019; 48:20180162.
- 45Barchetti F, Stagnitti A, Glorioso M, et al. Static and dynamic MR imaging in the evaluation of temporomandibular disorders. Eur Rev Med Pharmacol Sci 2014; 18: 2983-2987.
- 46Cassetta M, Barchetti F, Pranno N, Marini M. Comparing proton density and turbo spin echo T-2 weighted static sequences with dynamic half-Fourier single-shot TSE pulse sequence at 3.0 T in diagnosis of temporomandibular joint disorders: A prospective study. Dentomaxillofac Radiol 2014; 43:20130387.
- 47Khoo MM, Tyler PA, Saifuddin A, Padhani AR. Diffusion-weighted imaging (DWI) in musculoskeletal MRI: A critical review. Skeletal Radiol 2011; 40: 665-681.
- 48Le Bihan D. What can we see with IVIM MRI? Neuroimage 2019; 187: 56-67.
- 49Oudeman J, Nederveen AJ, Strijkers GJ, Maas M, Luijten PR, Froeling M. Techniques and applications of skeletal muscle diffusion tensor imaging: A review. J Magn Reson Imaging 2016; 43: 773-788.
- 50Chikui T, Shiraishi T, Ichihara T, et al. Effect of clenching on T2 and diffusion parameters of the masseter muscle. Acta Radiol 2010; 51: 58-63.
- 51Sawada E, Kaneda T, Sakai O, et al. Increased apparent diffusion coefficient values of masticatory muscles on diffusion-weighted magnetic resonance imaging in patients with temporomandibular joint disorder and unilateral pain. J Oral Maxillofac Surg 2019; 77: 2223-2229.
- 52Ngamsom S, Nakamura S, Sakamoto J, Kotaki S, Tetsumura A, Kurabayashi T. The intravoxel incoherent motion MRI of lateral pterygoid muscle: A quantitative analysis in patients with temporomandibular joint disorders. Dentomaxillofac Radiol 2017; 46:20160424.
- 53Sasaki M, Sumi M, Van Cauteren M, Obara M, Nakamura T. Intravoxel incoherent motion imaging of masticatory muscles: Pilot study for the assessment of perfusion and diffusion during clenching. Am J Roentgenol 2013; 201: 1101-1107.
- 54Benavides E, Bilgen M, Al-Hafez B, Alrefae T, Wang Y, Spencer P. High-resolution magnetic resonance imaging and diffusion tensor imaging of the porcine temporomandibular joint disc. Dentomaxillofac Radiol 2009; 38: 148-155.
- 55Falcinelli C, Li Z, Lam WW, Stanisz GJ, Agur AM, Whyne CM. Diffusion-tensor imaging versus digitization in reconstructing the masseter architecture. J Biomech Eng 2018; 140: 111010–111016.
- 56Liu S, Wang M, Ai T, et al. In vivo morphological and functional evaluation of the lateral pterygoid muscle: A diffusion tensor imaging study. Br J Radiol 2016; 89:20160041.
- 57Nastro E, Bonanno L, Catalfamo L, et al. Diffusion tensor imaging reveals morphological alterations of the lateral pterygoid muscle in patients with mandibular asymmetry. Dentomaxillofac Radiol 2018; 47:20170129.
- 58Mormina E, Granata F, Gaeta M, et al. Microstructural investigation of masticatory muscles: A pre- and post-treatment diffusion tensor imaging study in a bruxism case. Dentomaxillofac Radiol 2018; 47:20170275.
- 59Sano T, Westesson P-L. Magnetic resonance imaging of the temporomandibular joint: Increased T2 signal in the retrodiskal tissue of painful joints. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 1995; 79: 511-516.
- 60Gold GE, Chen CA, Koo S, Hargreaves BA, Bangerter NK. Recent advances in MRI of articular cartilage. Am J Roentgenol 2009; 193: 628-638.
- 61Welsch GH, Sebastian Krinner FFH, Trattnig S. T2 and T2* mapping. Curr Radiol Rep 2014; 2: 60–69.
10.1007/s40134-014-0060-1 Google Scholar
- 62Mosher TJ, Smith HE, Collins C, et al. Change in knee cartilage T2 at MR imaging after running: A feasibility study. Radiology 2005; 234: 245-249.
- 63Bristela M, Skolka A, Eder J, et al. T2 mapping with 3.0T MRI of the temporomandibular joint disc of patients with disc dislocation. Magn Reson Imaging 2019; 58: 125-134.
- 64Ariji Y, Sakuma S, Izumi M, et al. Ultrasonographic features of the masseter muscle in female patients with temporomandibular disorder associated with myofascial pain. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2004; 98: 337-341.
- 65Nikkuni Y, Nishiyama H, Hyayashi T. The relationship between masseter muscle pain and T2 values in temporomandibular joint disorders. Oral Surg Oral Med Oral Pathol Oral Radiol 2018; 126: 349-354.
- 66Yanagisawa O, Takahashi H, Fukubayashi T. Effects of different cooling treatments on water diffusion, microcirculation, and water content within exercised muscles: Evaluation by magnetic resonance T2-weighted and diffusion-weighted imaging. J Sports Sci 2010; 28: 1157-1163.
- 67Shigeno K, Sasaki Y, Otonari-Yamamoto M, Ohata H, Shibahara T. Evaluating the mandibular condyles of patients with osteoarthritis for bone marrow abnormalities using magnetic resonance T2 mapping. Oral Radiol 2019; 35: 272-279.
- 68Cao Y, Xia C, Wang S, He S, Wamalwa P, Chen S. Application of magnetic resonance T2 mapping in the temporomandibular joints. Oral Surg Oral Med Oral Pathol Oral Radiol 2012; 114: 644-649.
- 69Schmid-Schwap M, Bristela M, Pittschieler E, et al. Biochemical analysis of the articular disc of the temporomandibular joint with magnetic resonance T2 mapping: A feasibility study. Clin Oral Investig 2014; 18: 1865-1871.
- 70Kakimoto N, Shimamoto H, Kitisubkanchana J, et al. T2 relaxation times of the retrodiscal tissue in patients with temporomandibular joint disorders and in healthy volunteers: A comparative study. Oral Surg Oral Med Oral Pathol Oral Radiol 2019; 128: 311-318.
- 71Eder J, Tonar Z, Schmid-Schwap M, et al. Regional collagen fiber network in the articular disc of the human temporomandibular joint: Biochemical 3-Tesla quantitative magnetic resonance imaging compared to quantitative histologic analysis of fiber arrangement. J Oral Facial Pain Headache 2018; 32: 266-276.
- 72Kakimoto N, Shimamoto H, Chindasombatjaroen J, et al. Comparison of the T2 relaxation time of the temporomandibular joint articular disk between patients with temporomandibular disorders and asymptomatic volunteers. Am J Neuroradiol 2014; 35: 1412-1417.
- 73Mars M, Chelli M, Tbini Z, Ladeb F, Gharbi S. MRI T2 mapping of knee articular cartilage using different acquisition sequences and calculation methods at 1.5 Tesla. Med Princ Pract 2018; 27: 443-450.
- 74Reichert IL, Robson MD, Gatehouse PD, et al. Magnetic resonance imaging of cortical bone with ultrashort TE pulse sequences. Magn Reson Imaging 2005; 23: 611-618.
- 75Carl M, Sanal HT, Diaz E, et al. Optimizing MR signal contrast of the temporomandibular joint disk. J Magn Reson Imaging 2011; 34: 1458-1464.
- 76Chang EY, Du J, Chung CB. UTE imaging in the musculoskeletal system. J Magn Reson Imaging 2015; 41: 870-883.
- 77Weiger M, Pruessmann K. MRI with zero echo time. eMagRes 2012; 1: 311–322.
- 78Larson PE, Han M, Krug R, et al. Ultrashort echo time and zero echo time MRI at 7T. Magn Reson Mater Phys Biol Med 2016; 29: 359-370.
10.1007/s10334-015-0509-0 Google Scholar
- 79Sanal HT, Bae WC, Pauli C, et al. 3T MRI of the temporomandibular joint disc: Feasibility of novel quantitative MR evaluation using histologic and biomechanical reference standards. J Orofac Pain 2011; 25: 345.
- 80Bae WC, Tafur M, Chang EY, et al. High-resolution morphologic and ultrashort time-to-echo quantitative magnetic resonance imaging of the temporomandibular joint. Skeletal Radiol 2016; 45: 383-391.
- 81Geiger D, Bae WC, Statum S, Du J, Chung CB. Quantitative 3D ultrashort time-to-echo (UTE) MRI and micro-CT (muCT) evaluation of the temporomandibular joint (TMJ) condylar morphology. Skeletal Radiol 2014; 43: 19-25.
- 82Pittschieler E, Szomolanyi P, Schmid-Schwap M, et al. Delayed gadolinium-enhanced MRI of the fibrocartilage disc of the temporomandibular joint — A feasibility study. Magn Reson Imaging 2014; 32: 1223-1229.
- 83Eder J, Szomolanyi P, Schmid-Schwap M, et al. Early diagnosis of degenerative changes in the articular/fibrocartilaginous disc of the temporomandibular joint in patients with temporomandibular disorders using delayed gadolinium-enhanced MRI at 3 Tesla — Preliminary results. Magn Reson Imaging 2020; 67: 24-27.
- 84Tasali N, Cubuk R, Aricak M, et al. Temporomandibular joint (TMJ) pain revisited with dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI). Eur J Radiol 2012; 81: 603-608.
- 85Schraml C, Schwenzer NF, Martirosian P, Claussen CD, Schick F. Temporal course of perfusion in human masseter muscle during isometric contraction assessed by arterial spin labeling at 3T. Magma 2011; 24: 201-209.