Amidrazones and 2-Acetylcyclopentanone in the Synthesis of Cyclopenta[e][1,3,4]Oxadiazepines
Corresponding Author
Ashraf A. Aly
Department of Chemistry, Faculty of Science, Minia University, El-Minia, 6159 Egypt
E-mail: [email protected]Search for more papers by this authorEsam A. Ishak
Department of Chemistry, Faculty of Science, Al-Azhar University, Assiut, Egypt
Search for more papers by this authorMohamed Ramadan
Department of Organic Chemistry, Faculty of Pharmacy, Al-Azhar University, Assiut, Egypt
Search for more papers by this authorN. A. A. Elkanzi
Department of Chemistry, College of Science, Aswan University, Aswan, 81528 Egypt
Search for more papers by this authorAhmed A. M. El-Reedy
Department of Basic and Applied Science, Faculty of Oral and Dental Medicine, Nahda University, Beni-Suef, Egypt
Search for more papers by this authorCorresponding Author
Ashraf A. Aly
Department of Chemistry, Faculty of Science, Minia University, El-Minia, 6159 Egypt
E-mail: [email protected]Search for more papers by this authorEsam A. Ishak
Department of Chemistry, Faculty of Science, Al-Azhar University, Assiut, Egypt
Search for more papers by this authorMohamed Ramadan
Department of Organic Chemistry, Faculty of Pharmacy, Al-Azhar University, Assiut, Egypt
Search for more papers by this authorN. A. A. Elkanzi
Department of Chemistry, College of Science, Aswan University, Aswan, 81528 Egypt
Search for more papers by this authorAhmed A. M. El-Reedy
Department of Basic and Applied Science, Faculty of Oral and Dental Medicine, Nahda University, Beni-Suef, Egypt
Search for more papers by this authorAbstract
Amidrazones reacted with 2-acetylcyclopentanone at room temperature to give cyclopenta[e]-[1,3,4]oxadiazepines. The structure of the obtained products was proved by IR, mass, and NMR spectra and elemental analyses. Two-dimensional NMR spectroscopy was used to differentiate between other possible isomers. The reaction mechanism is also discussed.
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