(Substituted Ylidene)Amino-2-Oxo-Indolylidene Thioureas and Bis(2-Oxo-Indolylidene)Urea from (Ylidene)Thiocarbonohydrazides and Isatylidene Malononitrile
Corresponding Author
Alaa A. Hassan
Chemistry Department, Faculty of Science, Minia University, El-Minia, 61519 Egypt
E-mail: [email protected]Search for more papers by this authorShaaban K. Mohamed
Chemistry Department, Faculty of Science, Minia University, El-Minia, 61519 Egypt
Chemistry and Environmental Division, Manchester Metropolitan University, Manchester, M1 5GD England
Search for more papers by this authorFathy F. Abdel-Latif
Chemistry Department, Faculty of Science, Minia University, El-Minia, 61519 Egypt
Search for more papers by this authorSara M. Mostafa
Chemistry Department, Faculty of Science, Minia University, El-Minia, 61519 Egypt
Search for more papers by this authorMohamed Abdel-Aziz
Department of Medicinal Chemistry, Faculty of Pharmacy, Minia University, 61519 El-Minia, Egypt
Search for more papers by this authorJoel T. Mague
Department of Chemistry, Tulane University, New Orleans, LA, 70118 USA
Search for more papers by this authorMehmet Akkurt
Department of Physics, Faculty of Sciences, Erciyes University, 38039 Kayseri, Turkey
Search for more papers by this authorStefan Bräse
Institute of Organic Chemistry, Karlsruhe Institute of Technology, Fritz-Haber-Weg 6, 76131 Karlsruhe, Germany
Search for more papers by this authorMartin Nieger
Laboratory of Inorganic Chemistry, Department of Chemistry, University of Helsinki, P.O Box 55 (A. I. Virtasen aukio 1), 00014 Helsinki, Finland
Search for more papers by this authorCorresponding Author
Alaa A. Hassan
Chemistry Department, Faculty of Science, Minia University, El-Minia, 61519 Egypt
E-mail: [email protected]Search for more papers by this authorShaaban K. Mohamed
Chemistry Department, Faculty of Science, Minia University, El-Minia, 61519 Egypt
Chemistry and Environmental Division, Manchester Metropolitan University, Manchester, M1 5GD England
Search for more papers by this authorFathy F. Abdel-Latif
Chemistry Department, Faculty of Science, Minia University, El-Minia, 61519 Egypt
Search for more papers by this authorSara M. Mostafa
Chemistry Department, Faculty of Science, Minia University, El-Minia, 61519 Egypt
Search for more papers by this authorMohamed Abdel-Aziz
Department of Medicinal Chemistry, Faculty of Pharmacy, Minia University, 61519 El-Minia, Egypt
Search for more papers by this authorJoel T. Mague
Department of Chemistry, Tulane University, New Orleans, LA, 70118 USA
Search for more papers by this authorMehmet Akkurt
Department of Physics, Faculty of Sciences, Erciyes University, 38039 Kayseri, Turkey
Search for more papers by this authorStefan Bräse
Institute of Organic Chemistry, Karlsruhe Institute of Technology, Fritz-Haber-Weg 6, 76131 Karlsruhe, Germany
Search for more papers by this authorMartin Nieger
Laboratory of Inorganic Chemistry, Department of Chemistry, University of Helsinki, P.O Box 55 (A. I. Virtasen aukio 1), 00014 Helsinki, Finland
Search for more papers by this authorAbstract
A simple and efficient synthesis of (substituted ylidene)(2-oxoindolylidene)thiocarbohydrazones and bis(2-oxoindolylidene)urea was achieved by the reaction of (substituted ylidene)thiocarbonohydrazides with isatylidene malononitrile. Rational for this conversation involving the nucleophilic additions on the dicyanomethylene carbon atom is presented. The structures of the products have been confirmed by using spectral and single-crystal X-ray analyses.
Supporting Information
Crystallographic data (excluding structure factors) for the structure reported in this work have been deposited with Cambridge Crystallographic Data Center as supplementary publication no CCDC-1404594 (5e) and CCDC-1408760 (6). Copies of the data can be obtained free of charge on application to the Director, CCDC, 12 Union Road, Cambridge CB2 1EZ, UK (fax: +44(1223) 336 033: e-mail: [email protected]
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