Wear resistance of poly(2-methacryloyloxyethyl phosphorylcholine)-grafted carbon fiber reinforced poly(ether ether ketone) liners against metal and ceramic femoral heads
Shihori Yamane
Department of Materials Engineering, School of Engineering, The University of Tokyo, Bunkyo-ku, Tokyo, 113-8656 Japan
Division of Science for Joint Reconstruction, Graduate School of Medicine, The University of Tokyo, Bunkyo-ku, Tokyo, 113-8655 Japan
Medical R&D Center, Corporate R&D Group, KYOCERA Corporation, Yodogawa-ku, Osaka, 532-0003 Japan
Search for more papers by this authorMasayuki Kyomoto
Department of Materials Engineering, School of Engineering, The University of Tokyo, Bunkyo-ku, Tokyo, 113-8656 Japan
Division of Science for Joint Reconstruction, Graduate School of Medicine, The University of Tokyo, Bunkyo-ku, Tokyo, 113-8655 Japan
Medical R&D Center, Corporate R&D Group, KYOCERA Corporation, Yodogawa-ku, Osaka, 532-0003 Japan
Search for more papers by this authorToru Moro
Division of Science for Joint Reconstruction, Graduate School of Medicine, The University of Tokyo, Bunkyo-ku, Tokyo, 113-8655 Japan
Search for more papers by this authorMasami Hashimoto
Materials Research and Development Laboratory, Japan Fine Ceramics Center, Atsuta-ku, Nagoya, 456-8587 Japan
Search for more papers by this authorYoshio Takatori
Division of Science for Joint Reconstruction, Graduate School of Medicine, The University of Tokyo, Bunkyo-ku, Tokyo, 113-8655 Japan
Search for more papers by this authorSakae Tanaka
Department of Orthopaedic Surgery, Faculty of Medicine, The University of Tokyo, Bunkyo-ku, Tokyo, 113-8655 Japan
Search for more papers by this authorCorresponding Author
Kazuhiko Ishihara
Department of Materials Engineering, School of Engineering, The University of Tokyo, Bunkyo-ku, Tokyo, 113-8656 Japan
Correspondence to: K. Ishihara, e-mail: [email protected]Search for more papers by this authorShihori Yamane
Department of Materials Engineering, School of Engineering, The University of Tokyo, Bunkyo-ku, Tokyo, 113-8656 Japan
Division of Science for Joint Reconstruction, Graduate School of Medicine, The University of Tokyo, Bunkyo-ku, Tokyo, 113-8655 Japan
Medical R&D Center, Corporate R&D Group, KYOCERA Corporation, Yodogawa-ku, Osaka, 532-0003 Japan
Search for more papers by this authorMasayuki Kyomoto
Department of Materials Engineering, School of Engineering, The University of Tokyo, Bunkyo-ku, Tokyo, 113-8656 Japan
Division of Science for Joint Reconstruction, Graduate School of Medicine, The University of Tokyo, Bunkyo-ku, Tokyo, 113-8655 Japan
Medical R&D Center, Corporate R&D Group, KYOCERA Corporation, Yodogawa-ku, Osaka, 532-0003 Japan
Search for more papers by this authorToru Moro
Division of Science for Joint Reconstruction, Graduate School of Medicine, The University of Tokyo, Bunkyo-ku, Tokyo, 113-8655 Japan
Search for more papers by this authorMasami Hashimoto
Materials Research and Development Laboratory, Japan Fine Ceramics Center, Atsuta-ku, Nagoya, 456-8587 Japan
Search for more papers by this authorYoshio Takatori
Division of Science for Joint Reconstruction, Graduate School of Medicine, The University of Tokyo, Bunkyo-ku, Tokyo, 113-8655 Japan
Search for more papers by this authorSakae Tanaka
Department of Orthopaedic Surgery, Faculty of Medicine, The University of Tokyo, Bunkyo-ku, Tokyo, 113-8655 Japan
Search for more papers by this authorCorresponding Author
Kazuhiko Ishihara
Department of Materials Engineering, School of Engineering, The University of Tokyo, Bunkyo-ku, Tokyo, 113-8656 Japan
Correspondence to: K. Ishihara, e-mail: [email protected]Search for more papers by this authorAbstract
Younger, active patients who undergo total hip arthroplasty (THA) have increasing needs for wider range of motion and improved stability of the joint. Therefore, bearing materials having not only higher wear resistance but also mechanical strength are required. Carbon fiber-reinforced poly(ether ether ketone) (CFR-PEEK) is known as a super engineering plastic that has great mechanical strength. In this study, we focused on poly(2-methacryloyloxyethyl phosphorylcholine) (PMPC)-grafted CFR-PEEK and investigated the effects of PMPC grafting and the femoral heads materials on the wear properties of CFR-PEEK liners. Compared with untreated CFR-PEEK, the PMPC-grafted CFR-PEEK surface revealed higher wettability and lower friction properties under aqueous circumstances. In the hip simulator wear test, wear particles generated from the PMPC-grafted CFR-PEEK liners were fewer than those of the untreated CFR-PEEK liners. There were no significant differences in the size and the morphology of the wear particles between the differences of PMPC-grafting and the counter femoral heads. Zirconia-toughened alumina (ZTA) femoral heads had significantly smoother surfaces compared to cobalt–chromium–molybdenum alloy femoral heads after the hip simulator test. Thus, we conclude that the bearing combination of the PMPC-grafted CFR-PEEK liner and ZTA head is expected to be a lifelong bearing interface in THA. © 2017 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 106B: 1028–1037, 2018.
REFERENCES
- 1 Kurtz SM. The origins of UHMWPE in total hip arthroplasty. In: SM Kurtz, editor. UHMWPE Biomaterials Handbook. Oxford: William Andrew; 2015. pp 33–44.
- 2 Merchau H, Herberts P, Eisler T, Garellick G, Soderman P. The Swedish total hip replacement register. J Bone Joint Surg Am 2002; 84: 2–20.
- 3 Jacobs JJ, Roebuck KA, Archibeck M, Hallab NJ, Glant TT. Osteolysis: Basic science. Clin Orthop Relat Res 2001; 393: 71–77.
- 4 Glant TT, Jacobs JJ, Molnar G, Shanbhag AS, Valyon M, Galante JO. Bone resorption activity of particulate-stimulated macrophages. J Bone Miner Res 1993; 8: 1071–1079.
- 5
Brach de Prever EM,
Bistolfi A,
Bracco P,
Costa L. UHMWPE for arthroplasty: Past or future? J Orthopaed Traumatol 2009; 10: 1–8.
10.1007/s10195-008-0038-y Google Scholar
- 6 Kyomoto M, Iwasaki Y, Moro T, Konno T, Miyaji F, Kawaguchi H, Takatori Y, Nakamura K, Ishihara K. High lubricious surface of cobalt-chromium-molybdenum alloy prepared by grafting poly(2-methacryloyloxyethyl phosphorylcholine). Biomaterials 2007; 28: 3121–3130.
- 7 McMinn DJ, Daniel J, Pynsent PB, Pradhan C. Mini-incision resurfacing arthroplasty of hip through the posterior approach. Clin Orthop Relat Res 2005; 441: 91–98.
- 8 Muratoglu OK, Bragdon CR, O'Connor DO, Jasty M, Harris WH. A novel method of cross-linking ultra-high-molecular-weight polyethylene to improve wear, reduce oxidation, and retain mechanical properties. Recipient of the 1999 HAP Paul Award. J Arthroplasty 2001; 16: 149–160.
- 9 Chevalier J, Grandjean S, Kuntz M, Pezzotti G. On the kinetics and impact of tetragonal to monoclinic transformation in an alumina/zirconia composite for arthroplasty applications. Biomaterials 2009; 30: 5279–5282.
- 10 Moro T, Kawaguchi H, Ishihara K, Kyomoto M, Karita T, Ito H, Nakamura K, Takatori Y. Wear resistance of artificial hip joints with poly(2-methacryloyloxyethyl phosphorylcholine) grafted polyethylene: comparisons with the effect of polyethylene cross-linking and ceramic femoral heads. Biomaterials 2009; 30: 2995–3001.
- 11 Moro T, Takatori Y, Ishihara K, Konno T, Takigawa Y, Matsushita T, Chung U, Nakamura K, Kawaguchi H. Surface grafting of artifi cial joints with a biocompatible polymer for preventing periprosthetic osteolysis. Nature Mater 2004; 3: 829–836.
- 12 Takatori Y, Moro T, Ishihara K, Kamogawa M, Oda H, Umeyama T, Kim YT, Ito H, Kyomoto M, Tanaka T, Kawaguchi H, Tanaka S. Clinical and radiographic outcomes of total hip replacement with poly(2-methacryloyloxyethyl phosphorylcholine)-grafted highly cross-linked polyethylene liners: three-year results of a prospective consecutive series. Mod Rheumatol 2015; 25: 286–291.
- 13 Ueda T, Oshida H, Kurita K, Ishihara K, Nakabayashi N. Preparation of 2-methacryloyloxyethyl phosphorylcholine copolymers with alkyl methacrylates and their blood compatibility. Polym J 1992; 24: 1259–1269.
- 14 Ishihara K. Bioinspired phospholipid polymer biomaterials for making high performance artificial organs. Sci Technol Adv Mater 2000; 1: 131–138.
- 15 Iwasaki Y, Ishihara K. Cell membrane-inspired phospholipid polymers for developing medical devices with excellent biointerfaces. Sci Technol Adv Mater 2012; 13: 046101.
- 16 Moro T, Takatori Y, Ishihara K, Nakamura K, Kawaguchi H. Grafting of biocompatible polymer for longevity of artificial hip joints. Clin Orthop Relat Res 2006; 453: 58–63.
- 17 Kyomoto M, Moro T, Konno T, Takadama H, Yamawaki N, Kawaguchi H, Takatori Y, Nakamura K, Ishihara, K. Enhanced wear resistance of modified cross-linked polyethylene by grafting with poly(2-methacryloyloxyethyl phosphorylcholine). J Biomed Mater Res A 2007; 82: 10–17.
- 18 Kyomoto M, Moro T, Takatori Y, Kawaguchi H, Ishihara K. Cartilage-mimicking, high-density brush structure improves wear resistance of crosslinked polyethylene: a pilot study. Clin Orthop Relat Res 2011; 469: 2327–2336.
- 19 Vries LM, Sturkenboom MCJM, Verhaar JAN, Kingma JH, Stricker BHC. Complications after hip arthroplasty and the association with hospital procedure volume. Acta Orthop 2011; 82: 545–552.
- 20 Banerjee S, Pivec R, Issa K, Kapadia BH, Khanuja HS, Mont MA. Large-diameter femoral heads in total hip arthroplasty: An evidence-based review. Am J Orthop 2014; 43: 506–512.
- 21 Kurtz SM. Application of polyaryletheretherketone in spinal implants: Fusion and motion. In: SM Kurtz, editor. PEEK Biomaterials Handbook. Oxford: William Andrew; 2011. pp 201–220.
- 22 Kyomoto M, Ishihara K. Self-initiated surface graft polymerization of 2-methacryloyloxyethyl phosphorylcholine on poly(ether-ether-ketone) by photo-irradiation. ACS Appl Mater Interfaces 2009; 1: 537–542.
- 23 Kyomoto M, Moro T, Takatori Y, Kawaguchi H, Nakamura K, Ishihara K. Novel self-initiated surface grafting with poly(2-methacryloyloxyethyl phosphorylcholine) on poly(ether-ether-ketone) biomaterials. Biomaterials 2010; 31: 1017–1024.
- 24 Kyomoto M, Moro T, Yamane S, Hashimoto M, Takatori Y, Ishihara K. Poly(ether-ether-ketone) orthopedic bearing surface modified by self-initiated surface grafting of poly(2-methacryloyloxyethyl phosphorylcholine). Biomaterials 2013; 34: 7829–7839.
- 25
Kurtz SM,
Nevelos J. Arthroplasty bearing surfaces. In: SM Kurtz, editor. PEEK Biomaterials Handbook. London: Elsevier; 2012. pp 261–276.
10.1016/B978-1-4377-4463-7.10016-8 Google Scholar
- 26 Field RE, Rajakulendran K, Eswaramoorthy VK, Rshton N. Three year prospective clinical and radiological results of a new flexible horseshoe acetabular cup. Hip Int 2012; 22: 598–606.
- 27 Ishihara K, Ueda T, Nakabayashi N. Preparation of phospholipid polymers and their properties as polymer hydrogel membranes. Polym J 1990; 22: 355–360.
- 28 Kyomoto M, Moro T, Miyaji F, Konno T, Hashimoto M, Kawaguchi H, Takatori Y, Nakamura K, Ishihara K. Effect of 2-methacryloyloxyethyl phosphorylcholine concentration on photo-induced graft polymerization of polyethylene in reducing the wear of orthopaedic bearing surface. J Biomed Mater Res A 2008; 86: 439–447.
- 29 Kyomoto M, Moro T, Konno T, Takadama H, Kawaguchi H, Takatori Y, Nakamura K, Yamawaki N, Ishihara K. Effects of photo-induced graft polymerization of 2-methacryloyloxyethyl phosphorylcholine on physical properties of cross-linked graft polyethylene in artificial hip joints. J Mater Sci Mater Med 2007; 18: 1809–1815.
- 30 Kyomoto M, Moro T, Yamane S, Hashimoto M, Takatori Y, Ishihara K. Effect of UV-irradiation intensity on graft polymerization of 2-methacryloyloxyethyl phosphorylcholine on orthopedic bearing substrate. J Biomed Mater Res A 2014; 102: 3012–3023.
- 31 Scholes C, Inman IA, Unsworsh A, Jones E. Tribological assessment of a flexible carbon-fiber-reinforced poly(ether-ether-ketone) acetabular cup articulating against alumina femoral head. Proc Inst Mech Eng Part H J Eng Med 2008; 222: 273–283.
- 32 Brockett CL, John G, Williams S, Jin Z, Isaac GH, Fisher J. Wear of ceramic-on-carbon fiber reinforced poly-ether ether ketone hip replacements. J Biomed Mater Res B 2012; 100B: 1459–1465.
- 33 Scholes C, Unsworsh A. The wear properties of CFR-PEEK-OPTIMA articulating against ceramic assessed on a multidirectional pin-on-plate machine. Proc Inst Mech Eng Part H J Eng Med 2007; 221: 281–289.
- 34 Evans A, Horton H, Unsworsh A, Briscoe A. The influence of normal stress on wear factors of carbon fibre-reinforced polyetheretherketone (PEEK-OPTIMA® Wear Performance) against zirconia toughened alumina (Biolox® delta ceramic). Proc Inst Mech Eng Part H J Eng Med 2014; 228: 587–592.
- 35 Natu S, Sidaginamale RP, Ghandhi J, Langton DJ, Nargol AVF. Adverse reactions to metal debris: Histopathological features of periprosthetic soft tissue reactions seen in association with failed metal on metal hip arthroplasties. J Clin Pathol 2012; 65: 409–418.
- 36
Nakanishi T,
Sasaki M,
Ikeda J,
Miyaji F,
Kondo M. mechanical and phase staility of zirconia toughened alumina. Key Eng Mater 2007; 19: 1267–1270.
10.4028/www.scientific.net/KEM.330-332.1267 Google Scholar
- 37 Oonishi H, Ueno M, Kim SC, Oonishi H, Iwamoto M, Kyomoto M. Ceramic versus cobalt chrome femoral components; wear of polyethylene insert in total knee prosthesis. J Arthroplasty 2009; 24: 374–381.
- 38 Green TR, Fisher J, Stone M, Wroblewski BM, Ingham E. Polyethylene particles of a “critical size” are necessary for the induction of cytokines by macrophages in vitro. Biomaterials 1998; 19: 2297–2302.
- 39
Jagar M,
Zilkens C,
Zanger K,
Krauspe R. Significance of nano- and microtopography for cell-surface interactions in orthopaedic implants. J Biomed Biotechnol 2007; 8: 1–19.
10.1155/2007/69036 Google Scholar
- 40 Utzschneider S, Becker F, Grupp TM, Sievers B, Paulus AC, Gottschalk O, Janson V. Inflammatory response against different carbon fiber-reinforced PEEK wear particles compared with UHMWPE in vivo. Acta Biomaterialia 2010; 6: 4296–4304.
- 41 Lorber V, Paulus AC, Buschmann A, Schmitt B, Grupp TM, Jansson V, Utzschneider S. Elevated cytokine expression of different PEEK wear particles compared to UHMWPE in vivo. J Mater Sci Mater Med 2014; 25: 141–149.
- 42 Wang QQ, Wu JJ, Unsworth A, Briscoe A, Smith MJ, Lowry C, Simpson D, Collins S. Biotribological study of large diameter ceramic-on-CFR-PEEK hip joint including fluid uptake, wear and frictional heating. J Mater Sci Mater Med 2012; 23: 1533–1542.
