Retracted: Bone healing in critical-size defects treated with new bioactive glass/calcium sulfate: A histologic and histometric study in rat calvaria
Retraction(s) for this article
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Retraction: Bone healing in critical-size defects treated with new bioactive glass/calcium sulfate: A histologic and histometric study in rat calvaria
- Volume 112Issue 6Journal of Biomedical Materials Research Part B: Applied Biomaterials
- First Published online: May 22, 2024
Corresponding Author
Maria J. H. Nagata
Division of Periodontics, Department of Surgery and Integrated Clinic, Dental School of Araçatuba, São Paulo State University-UNESP, Brazil
Division of Periodontics, Department of Surgery and Integrated Clinic, Dental School of Araçatuba, São Paulo State University - UNESP, BrazilSearch for more papers by this authorFlávia A. C. Furlaneto
Division of Periodontics, Department of Surgery and Integrated Clinic, Dental School of Araçatuba, São Paulo State University-UNESP, Brazil
Search for more papers by this authorAntonio J. Moretti
Department of Periodontology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina
Search for more papers by this authorJerry E. Bouquot
Department of Diagnostic Sciences, The University of Texas Health Science Center Dental Branch, Houston, Texas
Search for more papers by this authorChul W. Ahn
Department of Clinical Sciences, The University of Texas Southwestern Medical Center, Dallas, Texas
Search for more papers by this authorMichel R. Messora
Division of Periodontics, Department of Surgery and Integrated Clinic, Dental School of Araçatuba, São Paulo State University-UNESP, Brazil
Search for more papers by this authorStephen E. Fucini
Division of Periodontics, Department of Surgery and Integrated Clinic, Dental School of Araçatuba, São Paulo State University-UNESP, Brazil
Private Practice, Hanover, New Hampshire
Search for more papers by this authorValdir G. Garcia
Division of Periodontics, Department of Surgery and Integrated Clinic, Dental School of Araçatuba, São Paulo State University-UNESP, Brazil
Search for more papers by this authorAlvaro F. Bosco
Division of Periodontics, Department of Surgery and Integrated Clinic, Dental School of Araçatuba, São Paulo State University-UNESP, Brazil
Search for more papers by this authorCorresponding Author
Maria J. H. Nagata
Division of Periodontics, Department of Surgery and Integrated Clinic, Dental School of Araçatuba, São Paulo State University-UNESP, Brazil
Division of Periodontics, Department of Surgery and Integrated Clinic, Dental School of Araçatuba, São Paulo State University - UNESP, BrazilSearch for more papers by this authorFlávia A. C. Furlaneto
Division of Periodontics, Department of Surgery and Integrated Clinic, Dental School of Araçatuba, São Paulo State University-UNESP, Brazil
Search for more papers by this authorAntonio J. Moretti
Department of Periodontology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina
Search for more papers by this authorJerry E. Bouquot
Department of Diagnostic Sciences, The University of Texas Health Science Center Dental Branch, Houston, Texas
Search for more papers by this authorChul W. Ahn
Department of Clinical Sciences, The University of Texas Southwestern Medical Center, Dallas, Texas
Search for more papers by this authorMichel R. Messora
Division of Periodontics, Department of Surgery and Integrated Clinic, Dental School of Araçatuba, São Paulo State University-UNESP, Brazil
Search for more papers by this authorStephen E. Fucini
Division of Periodontics, Department of Surgery and Integrated Clinic, Dental School of Araçatuba, São Paulo State University-UNESP, Brazil
Private Practice, Hanover, New Hampshire
Search for more papers by this authorValdir G. Garcia
Division of Periodontics, Department of Surgery and Integrated Clinic, Dental School of Araçatuba, São Paulo State University-UNESP, Brazil
Search for more papers by this authorAlvaro F. Bosco
Division of Periodontics, Department of Surgery and Integrated Clinic, Dental School of Araçatuba, São Paulo State University-UNESP, Brazil
Search for more papers by this authorAbstract
This study analyzed histologically the influence of new spherical bioactive glass (NBG) particles with or without a calcium sulfate (CS) barrier on bone healing in surgically created critical-size defects (CSD) in rat calvaria. A CSD was made in each calvarium of 60 rats, which were divided into three groups: C (control): the defect was filled with blood clot only; NBG: the defect was filled with NBG only; and NBG/CS: the defect was filled with NBG covered by CS barrier. Subgroups were euthanized at 4 or 12 weeks. Amounts of new bone and remnants of implanted materials were calculated as percentages of total area of the original defect. Data were statistically analyzed. In contrast to Group C, thickness throughout defects in Groups NBG and NBG/CS was similar to the original calvarium. At 4 weeks, Group C had significantly more bone formation than Group NBG/CS. No significant differences were found between Group NBG and either Group C or Group NBG/CS. At 12 weeks, Group C had significantly more bone formation than Group NBG or NBG/CS. NBG particles, used with or without a CS barrier, maintained volume and contour of area grafted in CSD. Presence of remaining NBG particles might have accounted for smaller amount of new bone in Groups NBG and NBG/CS at 12 weeks post-operative. © 2010 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 2010.
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