Antibodies to HTLV-I in Nigerian blood-donors, their relatives and patients with leukaemias, lymphomas and other diseases
A. F. Fleming
Department of Haematology and Blood Transfusion, Ahmadu Bello University, Zaria, Nigeria
Search for more papers by this authorR. Maharajah
Department of Haematology and Blood Transfusion, Ahmadu Bello University, Zaria, Nigeria
Search for more papers by this authorM. Abraham
Department of Haematology and Blood Transfusion, Ahmadu Bello University, Zaria, Nigeria
Search for more papers by this authorA. G. Kulkarni
Department of Haematology and Blood Transfusion, Ahmadu Bello University, Zaria, Nigeria
Search for more papers by this authorS. R. Bhusnurmath
Department of Pathology, Ahmadu Bello University, Zaria, Nigeria
Search for more papers by this authorR. A. Okpara
Department of Haematology and Blood Transfusion, University of Calabar, Calabar, Nigeria
Search for more papers by this authorEka Williams
Department of Biological Sciences, University of Calabar, Calabar, Nigeria
Search for more papers by this authorI. Akinsete
Department of Haematology and Blood Transfusion, University of Lagos, Nigeria
Search for more papers by this authorJ. Schneider
Deutsches Primatenzentrum, Gottingen, Federal Republic of Germany
Search for more papers by this authorH. Bayer
Deutsches Primatenzentrum, Gottingen, Federal Republic of Germany
Search for more papers by this authorCorresponding Author
G. Hunsmann
Deutsches Primatenzentrum, Gottingen, Federal Republic of Germany
Deutsches Primatenzentrum, Kellnerweg 4, D-3400 Gottingen, Federal Republic of GermanySearch for more papers by this authorA. F. Fleming
Department of Haematology and Blood Transfusion, Ahmadu Bello University, Zaria, Nigeria
Search for more papers by this authorR. Maharajah
Department of Haematology and Blood Transfusion, Ahmadu Bello University, Zaria, Nigeria
Search for more papers by this authorM. Abraham
Department of Haematology and Blood Transfusion, Ahmadu Bello University, Zaria, Nigeria
Search for more papers by this authorA. G. Kulkarni
Department of Haematology and Blood Transfusion, Ahmadu Bello University, Zaria, Nigeria
Search for more papers by this authorS. R. Bhusnurmath
Department of Pathology, Ahmadu Bello University, Zaria, Nigeria
Search for more papers by this authorR. A. Okpara
Department of Haematology and Blood Transfusion, University of Calabar, Calabar, Nigeria
Search for more papers by this authorEka Williams
Department of Biological Sciences, University of Calabar, Calabar, Nigeria
Search for more papers by this authorI. Akinsete
Department of Haematology and Blood Transfusion, University of Lagos, Nigeria
Search for more papers by this authorJ. Schneider
Deutsches Primatenzentrum, Gottingen, Federal Republic of Germany
Search for more papers by this authorH. Bayer
Deutsches Primatenzentrum, Gottingen, Federal Republic of Germany
Search for more papers by this authorCorresponding Author
G. Hunsmann
Deutsches Primatenzentrum, Gottingen, Federal Republic of Germany
Deutsches Primatenzentrum, Kellnerweg 4, D-3400 Gottingen, Federal Republic of GermanySearch for more papers by this authorAbstract
Antibodies to HTLV-I have been detected in sera from 15 (2.0%) of 736 adult blood-donors in Nigeria, in 4 (20.0%) of 20 patients with chronic lymphatic leukaemia, 3 (10.0%) of 30 with non-Hodgkin's lymphoma, one of 12 with Burkitt's lymphoma and one of 7 with acute lymphoblastic leukaemia. The frequency of positivily was higher (3.6%) in the blood-donors from the guinea and wooded savanna of northern Nigeria than in those from the rain-forest and mangrove swamps of southern Nigeria (1.8% in Lagos and 0.7% in Calabar). Two of the 3 seropositive patients with lymphoma had clinical presentation and courses similar to those of Japanese and Caribbean patients with adult T-cell leukaemia/lymphoma.
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