Primary sclerosing cholangitis and Hodgkin's disease
Kevin M. Man
Department of Medicine, California Pacific Medical Center, San Francisco, California 94115
Search for more papers by this authorAnne Drejet
Department of Pathology, California Pacific Medical Center, San Francisco, California 94115
Search for more papers by this authorCorresponding Author
Emmet B. Keeffe M.D.
Department of Transplantation, California Pacific Medical Center, San Francisco, California 94115
Department of Medicine, California Pacific Medical Center, San Francisco, California 94115
California Pacific Medical Center, 2340 Clay Street, #423, San Francisco, CA 94115===Search for more papers by this authorRichard Garcia-Kennedy
Department of Pathology, California Pacific Medical Center, San Francisco, California 94115
Search for more papers by this authorJoanne C. Imperial
Department of Transplantation, California Pacific Medical Center, San Francisco, California 94115
Department of Medicine, California Pacific Medical Center, San Francisco, California 94115
Search for more papers by this authorCarlos O. Esquivel
Department of Transplantation, California Pacific Medical Center, San Francisco, California 94115
Search for more papers by this authorKevin M. Man
Department of Medicine, California Pacific Medical Center, San Francisco, California 94115
Search for more papers by this authorAnne Drejet
Department of Pathology, California Pacific Medical Center, San Francisco, California 94115
Search for more papers by this authorCorresponding Author
Emmet B. Keeffe M.D.
Department of Transplantation, California Pacific Medical Center, San Francisco, California 94115
Department of Medicine, California Pacific Medical Center, San Francisco, California 94115
California Pacific Medical Center, 2340 Clay Street, #423, San Francisco, CA 94115===Search for more papers by this authorRichard Garcia-Kennedy
Department of Pathology, California Pacific Medical Center, San Francisco, California 94115
Search for more papers by this authorJoanne C. Imperial
Department of Transplantation, California Pacific Medical Center, San Francisco, California 94115
Department of Medicine, California Pacific Medical Center, San Francisco, California 94115
Search for more papers by this authorCarlos O. Esquivel
Department of Transplantation, California Pacific Medical Center, San Francisco, California 94115
Search for more papers by this authorAbstract
Three patients with primary sclerosing cholangitis and Hodgkin's disease, a previously unrecognized association, are reported. All three patients were men, and one patient had Crohn's disease of the colon. Primary sclerosing cholangitis was diagnosed 2, 11 and 17 yr before diagnosis of Hodgkin's disease in the three patients, and all three had advanced biliary cirrhosis prompting referral for liver transplantation. The symptoms of Hodgkin's disease were often masked by similar manifestations of primary sclerosing cholangitis, particularly symptoms of recurrent biliary sepsis. Hodgkin's disease is another disorder that may occur in patients with primary sclerosing cholangitis, particularly in the setting of advanced disease, and may be masked by the underlying hepatobiliary disease. (HEPATOLOGY 1993;18:1127-1131).
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