ATP-dependent transport systems for organic anions
Corresponding Author
Dr. Piotr Zimniak
Department of Medicine, University of Arkansas for Medical Sciences, Little Rock, Arkansas 72205
Department of Biochemistry and Molecular Biology, University of Arkansas for Medical Sciences, Little Rock, Arkansas 72205
Division of Gastroenterology, University of Arkansas for Medical Sciences, Slot 567, 4301 W. Markham, Little Rock, AR 72205===Search for more papers by this authorYogesh C. Awasthi
Department of Human Biological Chemistry and Genetics, University of Texas Medical Branch, Galveston, Texas 77555
Search for more papers by this authorCorresponding Author
Dr. Piotr Zimniak
Department of Medicine, University of Arkansas for Medical Sciences, Little Rock, Arkansas 72205
Department of Biochemistry and Molecular Biology, University of Arkansas for Medical Sciences, Little Rock, Arkansas 72205
Division of Gastroenterology, University of Arkansas for Medical Sciences, Slot 567, 4301 W. Markham, Little Rock, AR 72205===Search for more papers by this authorYogesh C. Awasthi
Department of Human Biological Chemistry and Genetics, University of Texas Medical Branch, Galveston, Texas 77555
Search for more papers by this author
References
- 1 Eilers M, Schatz G. Protein unfolding and the energetics of protein translocation across biological membranes. Cell 1988; 52: 481–483.
- 2 Baker KP, Schatz G. Mitochondrial proteins essential for viability mediate protein import into yeast mitochondria. Nature 1990; 349: 205–208.
- 3 Ames GF, Mimura CS, Shyamala V. Bacterial periplasmic permeases belong to a family of transport proteins operating from Escherichia coli to human: traffic ATPases. FEMS Microbiol Rev 1990; 6: 429–446.
- 4 Endicott JA, Ling V. The biochemistry of P-glycoprotein-mediated multidrug resistance. Annu Rev Biochem 1989; 58: 137–171.
- 5 Riordan JR, Rommens JM, Kerem B, Alon N, Rozmahel R, Grzelczak Z, Zielenski J, et al. Identification of the cystic fibrosis gene: cloning and characterization of complementary DNA. Science 1989; 245: 1066–1080.
- 6 Thomas PJ, Shenbagamurthi P, Ysern X, Pedersen PL. Cystic fibrosis transmembrane conductance regulator: nucleotide binding to a synthetic peptide. Science 1991; 251: 555–557.
- 7 Walker JE, Saraste M, Runswick MJ, Gay NJ. Distantly related sequences in the α- and β-subunits of ATP synthase, myosin, kinases and other ATP-requiring enzymes and a common nucleotide binding fold. EMBO J 1982; 1: 945–951.
- 8 Hyde SC, Emsley P, Hartshorn MJ, Mimmack MM, Gileadi U, Pearce SR, Gallagher MP, et al. Structural model of ATP-binding proteins associated with cystic fibrosis, multidrug resistance and bacterial transport. Nature 1990; 346: 362–365.
- 9 Dhir R, Gros P. Functional analysis of chimeric proteins constructed by exchanging homologous domains of two P-glycoproteins conferring distinct drug resistance profiles. Biochemistry 1992; 31: 6103–6110.
- 10 Kamimoto Y, Gatmaitan Z, Hsu J, Arias IM. The function of Gp170, the multidrug resistance gene product, in rat liver canalicular membrane vesicles. J Biol Chem 1989; 264: 11693–11698.
- 11 Arias IM. Multidrug resistance genes, p-glycoprotein and the liver. HEPATOLOGY 1990; 12: 159–165.
- 12 Kitamura T, Jansen P, Hardenbrook C, Kamimoto Y, Gatmaitan Z, Arias IM. Defective ATP-dependent bile canalicular transport of organic anions in mutant (TR-) rats with conjugated hyperbilirubinemia. Proc Natl Acad Sci USA 1990; 87: 3557–3561.
- 13 Muller M, Ishikawa T, Berger U, Klunemann C, Lucka L, Schreyer A, Kannicht C, et al. ATP-dependent transport of taurocholate across the hepatocyte canalicular membrane mediated by a 100-kDa glycoprotein binding ATP and bile salt. J Biol Chem 1991; 266: 18920–18926.
- 14 Inoue M, Kinne R, Tran T, Arias IM. Taurocholate transport by rat liver canalicular membrane vesicles: evidence for the presence of an Na+-independent transport system. J Clin Invest 1984; 73: 659–663.
- 15 Ruetz S, Fricker G, Hugentobler G, Winterhalter K, Kurz G, Meier PU. Isolation and characterization of the putative canalicular bile salt transport system of rat liver. J Biol Chem 1987; 262: 11324–11330.
- 16 Ruetz S, Hugentobler G, Meier PJ. Functional reconstitution of the canalicular bile salt transport system of rat liver. Proc Natl Acad Sci USA 1988; 85: 6147–6151.
- 17 Sippel CJ, Ananthanarayanan M, Suchy FJ. Isolation and characterization of the canalicular membrane bile acid transport protein of rat liver. Am J Physiol 1990; 258: G728–G737.
- 18 Anwer MS, Hegner D. Potassium is important for hepatic bile acid secretion [Abstract]. Gastroenterology 1982; 82: 1009.
- 19 Adachi Y, Kobayashi H, Kurumi Y, Shouji M, Kitano M, Yamamoto T. ATP-dependent taurocholate transport by rat liver canalicular membrane vesicles. HEPATOLOGY 1991; 14: 655–659.
- 20 Nishida T, Gatmaitan Z, Che M, Arias IM. Rat liver canalicular membrane vesicles contain an ATP-dependent bile acid transport system. Proc Natl Acad Sci USA 1991; 88: 6590–6594.
- 21 Wolters H, Kuipers F, Vonk RJ. ATP-dependent taurocholate transport in human liver plasma membrane vesicles [Abstract]. Gastroenterology 1992; 102: A910.
- 22 Akerboom TPM, Bilzer M, Sies H. Competition between transport glutathione disulfide (GSSG) and glutathione S-conjugates from perfused rat liver into bile. FEBS Lett 1982; 140: 73–76.
- 23 Inoue M, Akerboom TP, Sies H, Kinne R, Thao T, Arias IM. Biliary transport of glutathione S-conjugate by rat liver canalicular membrane vesicles. J Biol Chem 1984; 259: 4998–5002.
- 24 Nicotera P, Baldi C, Svensson S-A, Larsson R, Bellomo G, Orrenius S. Glutathione S-conjugates stimulate ATP hydrolysis in the plasma membrane fraction of rat hepatocytes. FEBS Lett 1985; 187: 121–125.
- 25 Nicotera P, Moore M, Bellomo G, Mirabelli F, Orrenius S. Demonstration and partial characterization of glutathione disulfide-stimulated ATPase activity in the plasma membrane fraction from rat hepatocytes. J Biol Chem 1985; 260: 1999–2002.
- 26 Kobayashi K, Sogame Y, Hayashi K, Nicotera P, Orrenius S. ATP stimulates the uptake of S-dinitrophenylglutathione by rat liver plasma membrane vesicles. FEBS Lett 1988; 240: 55–58.
- 27 Kunst M, Sies H, Akerboom TPM. ATP-stimulated uptake of S-(2,4-dinitrophenyl)glutathione by plasma membrane vesicles from rat liver. Biochim Biophys Acta 1989; 983: 123–125.
- 28 Ishikawa T, Mueller M, Kluenemann C, Schaub T, Keppler D. ATP-dependent primary active transport of cysteinyl leukotrienes across liver canalicular membrane: role of the ATP-dependent transport system for glutathione S-conjugates. J Biol Chem 1990; 265: 19279–19286.
- 29 Kobayashi K, Sogame Y, Hara H, Hayashi K. Mechanism of glutathione S-conjugate transport in canalicular and basolateral rat liver plasma membranes. J Biol Chem 1990; 265: 7737–7741.
- 30 Akerboom TPM, Narayanaswami V, Kunst M, Sies H. ATP. dependent S-(2,4-dinitrophenyl)glutathione transport in canalicular plasma membrane vesicles from rat liver. J Biol Chem 1991; 266: 13147–13152.
- 31 Nishida T, Hardenbrook C, Gatmaitan Z, Arias IM. ATP-dependent organic anion transport system in normal and TR- rat liver canalicular membranes. Am J Physiol 1992; 262: G629–G635.
- 32 Ou de Elferink RPJ, Ottenhoff R, Liefting W, De Haan J, Jansen PLM. Hepatobiliary transport of glutathione and glutathione conjugate in rats with hereditary hyperbilirubinemia. J Clin Invest 1989; 84: 476–483.
- 33 Ou de Elferink RPJ, Ottenhoff R, Liefting WGM, Schoemaker B, Groen AK, Jansen PLM. ATP-dependent efflux of GSSG and GS-conjugate from isolated rat hepatocytes. Am J Physiol 1990; 258: G699–G706.
- 34 Kobayashi K, Komatsu S, Nishi T, Hara H, Hayashi K. ATP-dependent transport for glucuronides in canalicular plasma membrane vesicles. Biochem Biophys Res Commun 1991; 176: 622–626.
- 35 Kuipers F, Radominska A, Zimniak P, Little JM, Havinga R, Vonk RJ, Lester R. Defective biliary secretion of bile acid 3-O-glucuronides in rats with hereditary conjugated hyperbilirubinemia. J Lipid Res 1989; 30: 1835–1845.
- 36 De Vries MH, Redegeld FAM, Koster AS, Noordhoek J, De Haan JG, Oude Elferink RPJ, Jansen PLM. Hepatic, intestinal and renal transport of 1-naphthol-β-glucuronide in mutant rats with hereditary-conjugated hyperbilirubinemia. Naunyn Schmiedebergs Arch Pharmacol 1989; 340: 588–592.
- 37 Ballatori N, Truong AT. Relation between biliary glutathione excretion and bile acid-independent bile flow. Am J Physiol 1989; 256: G22–G30.
- 38 Awasthi YC, Singhal SS, Gupta S, Ahmad H, Zimniak P, Radominska A, Lester R, et al. Purification and characterization of an ATPase from human liver which catalyzes ATP hydrolysis in presence of the conjugates of bilirubin, bile acids and glutathione. Biochem Biophys Res Commun 1991; 175: 1090–1096.
- 39 Jansen PL, Peters WH, Lamers WH. Hereditary chronic conjugated hyperbilirubinemia in mutant rats caused by defective hepatic anion transport. HEPATOLOGY 1985; 5: 573–579.
- 40 Kuipers F, Enserink M, Havinga R, Van der Steen ABM, Hardonk MJ, Fevery J, Vonk RJ. Separate transport systems for biliary secretion of sulphated and unsulphated bile acids in the rat. In: G Paumgartner, A Stiehl, W Gerok, eds. Trends in bile acid research (Falk symposium no. 52). Dordrecht, The Netherlands; Kluwer Academic Publishers, 1988: 143–152.
- 41 Kuipers F, Enserink M, Havinga R, van der Steen AB, Hardonk MJ, Fevery J, Vonk RJ. Separate transport systems for biliary secretion of sulfated and unsulfated bile acids in the rat. J Clin Invest 1988; 81: 1593–1599.
- 42 Takikawa H, Sano H, Narita T, Uchida Y, Yamanaka M, Horie T, Mikami T, et al. Biliary excretion of bile acid conjugates in a hyperbilirubinemic mutant Sprague-Dawley rat. HEPATOLOGY 1991; 14: 352–360.
- 43 Kitamura T, Alroy J, Gatmaitan Z, Inoue M, Mikami T, Jansen P, Arias IM. Defective biliary excretion of epinephrine metabolites in mutant (TR-) rats; relationship to the pathogenesis of black liver in the Dubin-Johnson syndrome and Corriedale sheep with an analogous excretory defect. HEPATOLOGY 1992; 15: 1154–1159.
- 44 Jansen PL, Groothuis GM, Peters WH, Meijer DF. Selective hepatobiliary transport defect for organic anions and neutral steroids in mutant rats with hereditary-conjugated hyperbilirubinemia. HEPATOLOGY 1987; 7: 71–76.
- 45 Nishida T, Gatmaitan Z, Che M, Arias IM. Two separate canalicular transport systems for nonbile acid organic anions; studies in normal and TR- rat canalicular membrane vesicles [Abstract]. HEPATOLOGY 1991; 14: 92A.
- 46 Ou de Elferink RPJ, Ottenhoff R, Radominska A, Hofmann AF, Kuipers F, Jansen PLM. Inhibition of glutathione-conjugate secretion from isolated hepatocytes by dipolar bile acids and other organic anions. Biochem J 1991; 274: 281–286.
- 47 Fernandez-Checa JC, Takikawa H, Horie T, Ookhtens M, Kaplowitz N. Canalicular transport of reduced glutathione in normal and mutant Eisai hyperbilirubinemic rats. J Biol Chem 1992; 267: 1667–1673
- 48 Griffiths JC, Sies H, Meier PJ, Akerboom TP. Inhibition of taurocholate efflux from rat hepatic canalicular membrane vesicles by glutathione disulfide. FEBS Lett 1987; 213: 34–38.
- 49 Ishikawa T. ATP/Mg2+-dependent cardiac transport system for glutathione S-conjugates: a study using rat heart sarcolemma vesicles. J Biol Chem 1989; 264: 17343–17348.
- 50 Schaub T, Ishikawa T, Keppler D. ATP-dependent leukotriene export from mastocytoma cells. FEBS Lett 1991; 279: 83–86.
- 51 Vincenzini MT, Favilli F, Stio M, Iantomasi T. Intestinal glutathione transport system: a possible detoxication role. Biochim Biophys Acta 1991; 1073: 571–579.
- 52 Roelofsen H, Ottenhoff R, Oude Elferink RP, Jansen PL. Hepatocanalicular organic-anion transport is regulated by protein kinase C. Biochem J 1991; 278: 637–641.
- 53 Board P, Nishida T, Gatmaitan Z, Che M, Arias IM. Erythrocyte membrane transport of glutathione conjugates and oxidized glutathione in the Dubin-Johnson syndrome and in rats with hereditary hyperbilirubinemia. HEPATOLOGY 1992; 15: 722–725.
- 54 Heijn M, Oude Elfering RPJ, Jansen PLM. ATP-dependent multispecific organic anion transport system in rat erythrocyte membrane vesicles. Am J Physiol 1992; 262: C104–C110.
- 55 Kondo T, Miyamoto K, Gasa S, Taniguchi N, Kawakami Y. Purification and characterization of glutathione disulfidestimulated Mg2+-ATPase from human erythrocytes. Biochem Biophys Res Commun 1989; 162: 1–8.
- 56 Kunst M, Sies H, Akerboom TPM. S-(4-Azidophenacyl)[35Slglutathione photoaffinity labeling of rat liver plasma membrane-associated proteins. Biochim Biophys Acta 1989; 982: 15–23.
- 57 Zimniak P, Ziller III SA, Panfil I, Radominska A, Wolters H, Kuipers F, Sharma R, et al. Identification of an anion-transport ATPase that catalyzes glutathione conjugate-dependent ATP hydrolysis in canalicular plasma membranes from normal rats and rats with conjugated hyperbilirubinemia (GY mutant). Arch Biochem Biophys 1992; 292: 534–538.
- 58 Zimniak P, Ziller III S, Radominska A, Blaauw M, Wolters H, Kuipers F, Saxena M, et al. Photoaffinity labeling and partial purification of a transporting glutathione conjugate-dependent ATPase from canalicular rat liver plasma membranes [Abstract]. FASEB J 1992; 6: A117.
- 59 Zimniak P, Ziller III S, Radominska A, Blaauw M, Wolters H, Kuipers F, Saxena M, et al. Photoaffinity labeling with 8-azido[α-32P]ATP of the ATP-dependent glutathione conjugate transporter in canalicular plasma membranes form normal Wistar and GY mutant rats [Abstract]. HEPATOLOGY 1991; 14: 264A.
- 60 Srivastava SK, Beutler E. The transport of oxidized glutathione from human erythrocytes. J Biol Chem 1969; 244: 9–16.
- 61 Kondo T, Dale GL, Buetler E. Studies on glutathione transport utilizing inside-out vesicles prepared from human erythrocytes. Biochim Biophys Acta 1981; 645: 132–136.
- 62 Kondo T, Kawakami Y, Taniguchi N, Beutler E. Glutathione disulfide-stimulated Mg2+ -ATPase of human erythrocyte membranes. Proc Natl Acad Sci USA 1987; 84: 7373–7377.
- 63 Awasthi YC, Garg HS, Dao DD, Partridge CA, Srivastava SK. Enzymatic conjugation of erythrocyte glutathione with 1-chloro-2,4-dinitrobenzene: the fate of glutathione conjugate in erythrocytes and the effect of glutathione depletion on hemoglobin. Blood 1981; 58: 733–738.
- 64 Board PG. Transport of glutathione S-conjugate from human erythrocytes. FEBS Lett 1981; 124: 163–165.
- 65 Awasthi YC, Misra G, Rassin DK, Srivastava SK. Detoxification of xenobiotics of glutathione S-transferases in erythrocytes: the transport of the conjugate of glutathione and 1-chloro-2,4-dinitrobenzene. Br J Haematol 1983; 55: 419–425.
- 66 Kondo T, Murao M, Taniguchi M. Glutathione S-conjugate transport using inside-out vesicles from human erythrocytes. Eur J Biochem 1982; 125: 551–554.
- 67 LaBelle EF, Singh SV, Srivastava SK, Awasthi YC. Dinitrophenyl glutathione efflux from human erythrocytes is primary active ATP-dependent transport. Biochem J 1986; 238: 443–449.
- 68 Eckert K-G, Eyer P. Formation and transport of xenobiotic glutathione-S-conjugates in red cells. Biochem Pharmacol 1986; 35: 325–329.
- 69 LaBelle EF, Singh SV, Ahmad H, Wronski L, Srivastava SK, Awasthi YC. A novel dinitrophenylglutathione-stimulated ATPase is present in human erythrocyte membranes. FEBS Lett 1988; 288: 53–56.
- 70 Sharma R, Gupta S, Singh SV, Medh RD, Ahmad H, LaBelle EF, Awasthi YC. Purification and characterization of dinitrophenyl-glutathione ATPase of human erythrocytes and its expression in other tissues. Biochem Biophys Res Commun 1990; 171: 155–161.
- 71 Singhal SS, Sharma R, Gupta S, Ahmad H, Zimniak P, Radom inska A, Lester R, et al. The anionic conjugates of bilirubin and bile acids stimulate ATP hydrolysis by S-(dinitrophenyl) glutathione ATPase of human erythrocyte. FEBS Lett 1991; 281: 255–257.
- 72 LaBelle EF, Singh SV, Srivastava SK, Awasthi YC. Evidence for different transport systems for oxidized glutathione and S-dinitrophenyl glutathione in human erythrocytes. Biochem Biophys Res Commun 1986; 139: 538–544.
- 73 Sharma R, Gupta S, Ahmad H, Ansari GAS, Awasthi YC. Stimulation of a human erythrocyte membrane ATPase by glutathione conjugates. Toxicol Appl Pharmacol 1990; 104: 421–428.
- 74 Kasahara M, Hinkle PC. Reconstitution and purification of the D-glucose transporter from human erythrocytes. J Biol Chem 1977; 252: 7384–7390.
- 75 Saxena M, Singhal SS, Awasthi S, Singh SV, Labelle EF, Zimniak P, Awasthi YC. Dinitrophenyl S-glutathione ATPase purified from human muscle catalyzes ATP hydrolysis in the presence of leukotrienes. Arch Biochem Biophys 1992; 292: 534–538.