Reduction of intrapulmonary shunt and resolution of digital clubbing associated with primary biliary cirrhosis after liver transplantation
Corresponding Author
James K. Stoller
The Departments of Pulmonary Disease, The Cleveland Clinic Foundation, Cleveland, Ohio 44195
Department of Pulmonary Disease, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195–5038===Search for more papers by this authorDouglas Moodie
The Departments of Pulmonary Disease, The Cleveland Clinic Foundation, Cleveland, Ohio 44195
Search for more papers by this authorWilliam A. Schiavone
Departments of Cardiology, The Cleveland Clinic Foundation, Cleveland, Ohio 44195
Search for more papers by this authorDavid Vogt
Departments of Genral Surgery, The Cleveland Clinic Foundation, Cleveland, Ohio 44195
Search for more papers by this authorThomas Broughan
Departments of Genral Surgery, The Cleveland Clinic Foundation, Cleveland, Ohio 44195
Search for more papers by this authorEugene Winkelman
The Departments of Gastroenterology, The Cleveland Clinic Foundation, Cleveland, Ohio 44195
Search for more papers by this authorPatrice K. Rehm
Departments of Radiology, The Cleveland Clinic Foundation, Cleveland, Ohio 44195
Search for more papers by this authorWilliam D. Carey
The Departments of Gastroenterology, The Cleveland Clinic Foundation, Cleveland, Ohio 44195
Search for more papers by this authorCorresponding Author
James K. Stoller
The Departments of Pulmonary Disease, The Cleveland Clinic Foundation, Cleveland, Ohio 44195
Department of Pulmonary Disease, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195–5038===Search for more papers by this authorDouglas Moodie
The Departments of Pulmonary Disease, The Cleveland Clinic Foundation, Cleveland, Ohio 44195
Search for more papers by this authorWilliam A. Schiavone
Departments of Cardiology, The Cleveland Clinic Foundation, Cleveland, Ohio 44195
Search for more papers by this authorDavid Vogt
Departments of Genral Surgery, The Cleveland Clinic Foundation, Cleveland, Ohio 44195
Search for more papers by this authorThomas Broughan
Departments of Genral Surgery, The Cleveland Clinic Foundation, Cleveland, Ohio 44195
Search for more papers by this authorEugene Winkelman
The Departments of Gastroenterology, The Cleveland Clinic Foundation, Cleveland, Ohio 44195
Search for more papers by this authorPatrice K. Rehm
Departments of Radiology, The Cleveland Clinic Foundation, Cleveland, Ohio 44195
Search for more papers by this authorWilliam D. Carey
The Departments of Gastroenterology, The Cleveland Clinic Foundation, Cleveland, Ohio 44195
Search for more papers by this authorAbstract
This report describes a patient with marked hypoxemia caused by intrapulmonary shunt associated with primary biliary cirrhosis. Liver transplantation resulted in resolution of digital clubbing and reduction of intrapulmonary shunt as demonstrated by normalization of room air arterial blood gases, reduction in shunt fraction and normalization of the indocyanin-enhanced echocardiogram and perfusion lung scan.
This patient's course challenges the conventional notion that intrapulmonary shunting associated with chronic liver disease does not reverse after liver transplantation. (HEPATOLOGY 1990; 11: 54–58.)
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