Analysis of cost and outcomes in bony versus soft tissue midface free flap reconstruction
Corresponding Author
Angela Alnemri MD
Department of Otolaryngology – Head & Neck Surgery, Thomas Jefferson University, Philadelphia, Pennsylvania, USA
Correspondence
Angela Alnemri, Department of Otolaryngology – Head and Neck Surgery, Thomas Jefferson University Hospital, 925 Chestnut Street, 6th floor, Philadelphia, PA 19107, USA.
Email: [email protected]
Search for more papers by this authorRamez Philips MD
Department of Otolaryngology – Head & Neck Surgery, Thomas Jefferson University, Philadelphia, Pennsylvania, USA
Search for more papers by this authorSarah Sussman MD
Department of Otolaryngology – Head & Neck Surgery, Thomas Jefferson University, Philadelphia, Pennsylvania, USA
Search for more papers by this authorVivian Xu MD
Department of Otolaryngology – Head & Neck Surgery, Thomas Jefferson University, Philadelphia, Pennsylvania, USA
Search for more papers by this authorAlyssa Givens MD
Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania, USA
Search for more papers by this authorAnjali Patel BS
Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania, USA
Search for more papers by this authorBrian Swendseid MD
Department of Otolaryngology – Head and Neck Surgery, The Ohio State University, Columbus, Ohio, USA
Search for more papers by this authorAarti Agarwal MD
Department of Otolaryngology – Head & Neck Surgery, Thomas Jefferson University, Philadelphia, Pennsylvania, USA
Search for more papers by this authorScott Keith PhD
Division of Biostatistics, Thomas Jefferson University, Philadelphia, Pennsylvania, USA
Search for more papers by this authorAyako Shimada MS
Division of Biostatistics, Thomas Jefferson University, Philadelphia, Pennsylvania, USA
Search for more papers by this authorYamil Selman MD
Department of Otolaryngology – Head & Neck Surgery, Thomas Jefferson University, Philadelphia, Pennsylvania, USA
Search for more papers by this authorDavid M. Cognetti MD
Department of Otolaryngology – Head & Neck Surgery, Thomas Jefferson University, Philadelphia, Pennsylvania, USA
Search for more papers by this authorRyan Heffelfinger MD
Department of Otolaryngology – Head & Neck Surgery, Thomas Jefferson University, Philadelphia, Pennsylvania, USA
Search for more papers by this authorRichard Goldman MD
Department of Otolaryngology – Head & Neck Surgery, Thomas Jefferson University, Philadelphia, Pennsylvania, USA
Search for more papers by this authorAdam J. Luginbuhl MD
Department of Otolaryngology – Head & Neck Surgery, Thomas Jefferson University, Philadelphia, Pennsylvania, USA
Search for more papers by this authorMark K. Wax MD
Department of Otolaryngology – Head & Neck Surgery, Oregon Health & Science University, Portland, Oregon, USA
Search for more papers by this authorLarissa Sweeny MD
Department of Otolaryngology – Head and Neck Surgery, Louisiana State University Health Sciences Center, New Orleans, Louisiana, USA
Search for more papers by this authorJoseph M. Curry MD
Department of Otolaryngology – Head & Neck Surgery, Thomas Jefferson University, Philadelphia, Pennsylvania, USA
Search for more papers by this authorCorresponding Author
Angela Alnemri MD
Department of Otolaryngology – Head & Neck Surgery, Thomas Jefferson University, Philadelphia, Pennsylvania, USA
Correspondence
Angela Alnemri, Department of Otolaryngology – Head and Neck Surgery, Thomas Jefferson University Hospital, 925 Chestnut Street, 6th floor, Philadelphia, PA 19107, USA.
Email: [email protected]
Search for more papers by this authorRamez Philips MD
Department of Otolaryngology – Head & Neck Surgery, Thomas Jefferson University, Philadelphia, Pennsylvania, USA
Search for more papers by this authorSarah Sussman MD
Department of Otolaryngology – Head & Neck Surgery, Thomas Jefferson University, Philadelphia, Pennsylvania, USA
Search for more papers by this authorVivian Xu MD
Department of Otolaryngology – Head & Neck Surgery, Thomas Jefferson University, Philadelphia, Pennsylvania, USA
Search for more papers by this authorAlyssa Givens MD
Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania, USA
Search for more papers by this authorAnjali Patel BS
Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania, USA
Search for more papers by this authorBrian Swendseid MD
Department of Otolaryngology – Head and Neck Surgery, The Ohio State University, Columbus, Ohio, USA
Search for more papers by this authorAarti Agarwal MD
Department of Otolaryngology – Head & Neck Surgery, Thomas Jefferson University, Philadelphia, Pennsylvania, USA
Search for more papers by this authorScott Keith PhD
Division of Biostatistics, Thomas Jefferson University, Philadelphia, Pennsylvania, USA
Search for more papers by this authorAyako Shimada MS
Division of Biostatistics, Thomas Jefferson University, Philadelphia, Pennsylvania, USA
Search for more papers by this authorYamil Selman MD
Department of Otolaryngology – Head & Neck Surgery, Thomas Jefferson University, Philadelphia, Pennsylvania, USA
Search for more papers by this authorDavid M. Cognetti MD
Department of Otolaryngology – Head & Neck Surgery, Thomas Jefferson University, Philadelphia, Pennsylvania, USA
Search for more papers by this authorRyan Heffelfinger MD
Department of Otolaryngology – Head & Neck Surgery, Thomas Jefferson University, Philadelphia, Pennsylvania, USA
Search for more papers by this authorRichard Goldman MD
Department of Otolaryngology – Head & Neck Surgery, Thomas Jefferson University, Philadelphia, Pennsylvania, USA
Search for more papers by this authorAdam J. Luginbuhl MD
Department of Otolaryngology – Head & Neck Surgery, Thomas Jefferson University, Philadelphia, Pennsylvania, USA
Search for more papers by this authorMark K. Wax MD
Department of Otolaryngology – Head & Neck Surgery, Oregon Health & Science University, Portland, Oregon, USA
Search for more papers by this authorLarissa Sweeny MD
Department of Otolaryngology – Head and Neck Surgery, Louisiana State University Health Sciences Center, New Orleans, Louisiana, USA
Search for more papers by this authorJoseph M. Curry MD
Department of Otolaryngology – Head & Neck Surgery, Thomas Jefferson University, Philadelphia, Pennsylvania, USA
Search for more papers by this authorPoster presentation at the American Head and Neck Society 10th International Conference on Head and Neck Cancer “Survivorship through Quality and Innovation,” 22–25 July 2021.
Abstract
Background
Outcomes and cost of soft tissue versus bony midface free flap reconstruction (MR) with and without virtual surgical planning (VSP) were evaluated.
Methods
Retrospective review of MR including ischemic time (IT), operative duration (OD), length of stay (LOS), and total cost (TC). Eighty-one soft tissue and 76 bony MR (VSP = 23) were reviewed.
Results
Bony MR was used for higher complexity defects (p = 0.003) and was associated with higher IT (p < 0.001), OD (p < 0.001), LOS (p = 0.032), and TC (p < 0.001). VSP was associated with a mean 111.2 ± 37.9 minute reduction in OD (p = 0.004) compared to non-VSP bony flaps. VSP was associated with higher itemized cost, but no increase in TC (p = 0.327).
Conclusions
Bony MR was used for higher complexity MR and was associated with increased TC, LOS, OD, and IT. VSP shortened OD with no significant increase in TC.
CONFLICT OF INTEREST
The authors declare that there is no conflict of interest that could be perceived as prejudicing the impartiality of the research reported.
Open Research
DATA AVAILABILITY STATEMENT
The data that support the findings of this study are available from the corresponding author upon reasonable request.
Supporting Information
Filename | Description |
---|---|
hed27112-SUP-0001-Tables.pdfPDF document, 65 KB | Table S1 Breakdown of Cost Categories by UB Revenue Codes. Table S2 Descriptive statistics summary of total cost by Brown & Shaw classification, n = 157. Table S3 Descriptive statistics summary of total cost by Santamaria & Cordeiro classification, n = 157. |
Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
REFERENCES
- 1Swendseid BP, Roden DF, Vimawala S, et al. Virtual surgical planning in subscapular system free flap reconstruction of midface defects. Oral Oncol. 2020; 101:104508.
- 2Eskander A, Kang SY, Teknos TN, Old MO. Advances in midface reconstruction: beyond the reconstructive ladder. Curr Opin Otolaryngol Head Neck Surg. 2017; 25: 422-430.
- 3Futran ND, Wadsworth JT, Villaret D, Farwell DG. Midface reconstruction with the fibula free flap. Arch Otolaryngol Head Neck Surg. 2002; 128: 161-166.
- 4Hammer D, Vincent AG, Williams F, Ducic Y. Considerations in free flap reconstruction of the midface. Facial Plast Surg. 2021; 37: 759-770.
- 5Futran ND, Mendez E. Developments in reconstruction of midface and maxilla. Lancet Oncol. 2006; 7: 249-258.
- 6Rodby KA, Turin S, Jacobs RJ, et al. Advances in oncologic head and neck reconstruction: systematic review and future considerations of virtual surgical planning and computer aided design/computer aided modeling. J Plast Reconstr Aesthet Surg. 2014; 67: 1171-1185.
- 7Moore EJ, Price DL, Van Abel KM, et al. Association of virtual surgical planning with external incisions in complex maxillectomy reconstruction. JAMA Otolaryngol Head Neck Surg. 2021; 147: 526-531.
- 8Navarro Cuéllar C, Martínez EB, Navarro Cuéllar I, et al. Primary maxillary reconstruction with fibula flap and dental implants: a comparative study between virtual surgical planning and standard surgery in class IIC defects. J Oral Maxillofac Surg. 2021; 79: 237-248.
- 9Sweeny L, Rosenthal EL, Light T, et al. Outcomes and cost implications of microvascular reconstructions of the head and neck. Head Neck. 2019; 41: 930-939.
- 10Gao LL, Basta M, Kanchwala SK, Serletti JM, Low DW, Wu LC. Cost-effectiveness of microsurgical reconstruction for head and neck defects after oncologic resection. Head Neck. 2017; 39: 541-547.
- 11Porter ME. What is value in health care? N Engl J Med. 2010; 363: 2477-2481.
- 12Brown JS, Shaw RJ. Reconstruction of the maxilla and midface: introducing a new classification. Lancet Oncol. 2010; 11: 1001-1008.
- 13Santamaria E, Cordeiro PG. Reconstruction of maxillectomy and midfacial defects with free tissue transfer. J Surg Oncol. 2006; 94: 522-531.
- 14 U.S. Bureau of Labor Statistics. Consumer Price Index for All Urban Consumers: Medical Care in U.S. City Average [CPIMEDSL]. FRED, Federal Reserve Bank of St. Louis; 2021 https://fred.stlouisfed.org/series/CPIMEDSL
- 15Wolff KD, Hölzle F, Wysluch A, Mücke T, Kesting M. Incidence and time of intraoperative vascular complications in head and neck microsurgery. Microsurgery. 2008; 28: 143-146.
- 16Wu CC, Lin PY, Chew KY, Kuo YR. Free tissue transfers in head and neck reconstruction: complications, outcomes and strategies for management of flap failure: analysis of 2019 flaps in single institute. Microsurgery. 2014; 34: 339-344.
- 17Han Z, Li J, Li H, Su M, Qin L. Single versus dual venous anastomoses of the free fibula osteocutaneous flap in mandibular reconstruction: a retrospective study. Microsurgery. 2013; 33: 652-655.
- 18Chang SY, Huang JJ, Tsao CK, et al. Does ischemia time affect the outcome of free fibula flaps for head and neck reconstruction? A review of 116 cases. Plast Reconstr Surg. 2010; 126: 1988-1995.
- 19Chiodo AA, Gur E, Pang CY, et al. The vascularized pig fibula bone flap model: effect of segmental osteotomies and internal fixation on blood flow. Plast Reconstr Surg. 2000; 105: 1004-1012.
- 20Sweeny L, Fuson AR, Curry JM. Current trends in midface reconstruction and use of virtual surgical planning. Plast Aesthet Res. 2021; 8: 18.
- 21Avraham T, Franco P, Brecht LE, et al. Functional outcomes of virtually planned free fibula flap reconstruction of the mandible. Plast Reconstr Surg. 2014; 134: 628e-634e.
- 22Chang EI, Jenkins MP, Patel SA, Topham NS. Long-term operative outcomes of preoperative computed tomography-guided virtual surgical planning for osteocutaneous free flap mandible reconstruction. Plast Reconstr Surg. 2016; 137: 619-623.
- 23Mazzola F, Smithers F, Cheng K, et al. Time and cost-analysis of virtual surgical planning for head and neck reconstruction: a matched pair analysis. Oral Oncol. 2020; 100:104491.
- 24Barr ML, Haveles CS, Rezzadeh KS, et al. Virtual surgical planning for mandibular reconstruction with the fibula free flap: a systematic review and meta-analysis. Ann Plast Surg. 2020; 84: 117-122.
- 25Padilla PL, Mericli AF, Largo RD, Garvey PB. Computer-aided design and manufacturing versus conventional surgical planning for head and neck reconstruction: a systematic review and meta-analysis. Plast Reconstr Surg. 2021; 148(1): 183-192.
- 26Fatima A, Hackman TG, Wood JS. Cost-effectiveness analysis of virtual surgical planning in mandibular reconstruction. Plast Reconstr Surg. 2019; 143: 1185-1194.