Volume 39, Issue 1 pp. 32-36
Original Article

Value of fine-needle aspiration in evaluating large thyroid nodules

Thibaut Raguin MD

Thibaut Raguin MD

Service ORL et Chirurgie Cervico-faciale, CHU de Strasbourg, Strasbourg Cedex, France

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Olivier Schneegans MD

Olivier Schneegans MD

Service de Médecine Nucléaire, Centre Paul Strauss, Strasbourg, France

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Jean-François Rodier MD

Jean-François Rodier MD

Service de Chirurgie Viscérale et Thyroïdienne, Clinique Saint-Anne, Strasbourg, France

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Pierre-Philippe Volkmar MD

Pierre-Philippe Volkmar MD

Service de Chirurgie Viscérale et Thyroïdienne, Clinique Saint-Anne, Strasbourg, France

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Eric Sauleau MD, PhD

Eric Sauleau MD, PhD

Service de Santé Publique, CHU de Strasbourg, France

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Christian Debry MD, PhD

Christian Debry MD, PhD

Service ORL et Chirurgie Cervico-faciale, CHU de Strasbourg, Strasbourg Cedex, France

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Guillaume Debonnecaze MD

Guillaume Debonnecaze MD

Service d'Otorhinolaryngologie et Chirurgie Cervico-faciale, CHU de Toulouse, Toulouse, France

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Jean-Pierre Ghnassia MD

Jean-Pierre Ghnassia MD

Service d'Anatomopathologie, Centre Paul Strauss, Strasbourg, France

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Agnès Dupret-Bories MD, PhD

Corresponding Author

Agnès Dupret-Bories MD, PhD

Service d'Otorhinolaryngologie et Chirurgie Cervico-faciale, Institut Universitaire du Cancer, Toulouse, France

Corresponding author: A. Dupret–Bories, Service d'Otorhinolaryngologie et Chirurgie Cervico-faciale, Institut Universitaire du Cancer, 1 avenue Irène Joliot Curie, 31059 Toulouse, France. E-mail: [email protected]Search for more papers by this author
First published: 14 June 2016
Citations: 7

This work was presented as a poster presentation during the 15th International Thyroid Congress, Lake Buena Vista, Florida, October 18–23, 2015.

ABSTRACT

Background

The American Thyroid Association (ATA) recommends using ultrasound-guided fine-needle aspiration (FNA) in order to evaluate supracentimetric and suspect thyroid nodules. The purpose of this study was to evaluate the effective use of FNA before surgery for nodules over 3 cm in diameter.

Methods

In this retrospective study, we analyzed the results of ultrasound-guided FNA and postoperative histological analysis in 843 nodules >3 cm.

Results

The FNA was informative in 42.6%. The correlation with the final histological analysis was 94.8% for benign nodules and 71.0% for malignant nodules. The FNA had a positive predictive value of 71%, a specificity of 97%, a sensitivity of 56%, and a 4.7% rate of false-negative results.

Conclusion

Because there is a nonnegligible FNA risk of error, notably allowing the evolution of a cancer in 1 of 20 cases, the FNA data should not delay surgical intervention for potentially suspect nodules >3 cm in diameter. © 2016 Wiley Periodicals, Inc. Head Neck 39: 32–36, 2017

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