Clinical Review
Systematic review of treatment and prognosis of sinonasal hemangiopericytoma†
Melanie Duval MDCM,
Euna Hwang MDCM,
Shaun J. Kilty MD, FRCSC,
Melanie Duval MDCM
Department of Otolaryngology–Head and Neck Surgery, The Ottawa Hospital, University of Ottawa, Ottawa, Ontario, Canada
Search for more papers by this authorEuna Hwang MDCM
Department of Otolaryngology–Head and Neck Surgery, The Ottawa Hospital, University of Ottawa, Ottawa, Ontario, Canada
Search for more papers by this authorCorresponding Author
Shaun J. Kilty MD, FRCSC
Department of Otolaryngology–Head and Neck Surgery, The Ottawa Hospital, University of Ottawa, Ottawa, Ontario, Canada
Department of Otolaryngology–Head and Neck Surgery, Ottawa Hospital, Ottawa, Ontario, CanadaSearch for more papers by this authorMelanie Duval MDCM,
Euna Hwang MDCM,
Shaun J. Kilty MD, FRCSC,
Melanie Duval MDCM
Department of Otolaryngology–Head and Neck Surgery, The Ottawa Hospital, University of Ottawa, Ottawa, Ontario, Canada
Search for more papers by this authorEuna Hwang MDCM
Department of Otolaryngology–Head and Neck Surgery, The Ottawa Hospital, University of Ottawa, Ottawa, Ontario, Canada
Search for more papers by this authorCorresponding Author
Shaun J. Kilty MD, FRCSC
Department of Otolaryngology–Head and Neck Surgery, The Ottawa Hospital, University of Ottawa, Ottawa, Ontario, Canada
Department of Otolaryngology–Head and Neck Surgery, Ottawa Hospital, Ottawa, Ontario, CanadaSearch for more papers by this author†
Presented at American Academy of Otololaryngology-Head and Neck Surgery Annual Meeting, September 2010.
Abstract
Background
This study was undertaken to determine the recurrence rate for open and endoscopic surgery and the clinical prognosis of this sinonasal tumor.
Methods
A systematic review of individual cases of sinonasal hemangiopericytoma was performed. A total of 97 articles were included in the study and reviewed to extract the relevant information about each case.
Results
In all, 194 cases of sinonasal hemangiopericytoma were identified. There were 53 recurrences (27.3%), 6 tumor-related deaths (3.1%), and 4 cases of metastases (2.1%). There was no significant difference between rate of recurrence for endoscopic or open resection (p = .06). Incomplete excision was the most important predictor of recurrence (odds ratio = 11.50, 95% confidence interval 3.76–36.82, p < .001). Radiotherapy may be advantageous in cases of incomplete surgical resection (p = .03).
Conclusions
Complete excision is essential to minimize tumor recurrence and radiotherapy may decrease the rate of recurrence in the case of incomplete resection. Current evidence does not suggest that open resection is superior to endoscopic resection. © 2012 Wiley Periodicals, Inc. Head Neck, 2013
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